Pividine

Description

Pividine Ointment (Povidone Iodine 5% Topical)

Indications:

Pividine Ointment is used for the treatment and prevention of skin infections. This includes:

• Treatment of:
  • Primary or secondary topical infections
  • Infected surgical incisions
  • Infected decubitus (pressure) or stasis ulcers
  • Pyodermas (skin infections characterized by pus)
  • Secondarily infected dermatoses (skin conditions)
  • Infected traumatic lesions (cuts, abrasions, wounds)
• Prevention of infection in:
  • Cuts
  • Abrasions
  • Wounds

Dosage and Administration:

• Adults:
  • For treatment of infection: Apply once or twice daily, or with each dressing change, for a maximum of 14 days.
  • For prevention of infection: Apply once or twice weekly for as long as necessary.
  • Application: Clean and dry the affected area before applying the ointment directly. The treated area may be covered with a dressing or bandage.
• Pividine Powder: Apply as often as directed. May be covered with a dressing or bandage.

Contraindications:

• Regular use is contraindicated in individuals with pre-existing thyroid disorders, including nodular colloid goitre, endemic goitre, and Hashimoto’s thyroiditis.
• Not for use in infants under 2 years of age.
• Regular use should be avoided in patients receiving concurrent lithium therapy.

Precautions:

• Special caution is advised when applying regularly to broken skin in patients with pre-existing renal insufficiency.
• Use with caution during pregnancy and lactation.
• Use with caution in neonates.

Adverse Effects:

• Common: Local skin irritation and sensitivity, occasionally mild and transient burning or sticky sensation.
• Rare: Irritation or hypersensitivity reactions.
• Systemic Effects (due to iodine absorption): Application to large areas of denuded skin, severe burns, or large wounds may lead to systemic adverse effects such as:
  • Metabolic acidosis
  • Hypernatraemia (elevated blood sodium)
  • Impairment of renal function

Mechanism of Action:

Povidone-iodine is an iodophore that exhibits potent, broad-spectrum germicidal activity. It is effective against a wide range of bacteria, viruses, fungi, protozoa, and spores. Its microbicidal action involves the oxidation of cell constituents and the iodination and inactivation of proteins.

Product Information:

• Manufacturer: Lomus Pharmaceutical Pvt. Ltd.
• Generic Name: Povidone Iodine 5% Topical
• Availability: Available in Nepal.

Important Note:

The information provided on Pividine Ointment is for general knowledge and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.