Zenoxa-450mg

Uses: It is primarily used to treat and prevent partial-onset seizures in individuals with epilepsy. It can be used alone (monotherapy) in adults or as an add-on therapy (with other anti-epileptic medications) in adults and children (usually aged 4 years and older, though some sources mention 2 years and above for adjunctive therapy).

Oxcarbazepine works by blocking voltage-sensitive sodium channels in the brain, which helps to stabilize overactive nerve impulses and reduce abnormal electrical activity, thereby controlling seizures.

Dosage and Administration:

• Zenoxa-450mg is typically taken once or twice daily, with or without food, as prescribed by your doctor.
• It’s important to swallow the tablet whole and not chew, crush, or break it, especially if it’s an extended-release (OD or SR) formulation, to ensure the medication is released properly over time.
• The dose will be determined by your doctor, who may gradually increase it.
• Do not stop taking this medication suddenly without consulting your doctor, as this can lead to an increase in seizure frequency or withdrawal symptoms.

Side Effects: Common side effects can include:

• Dizziness
• Drowsiness, sleepiness, fatigue
• Headache
• Nausea, vomiting, abdominal pain, diarrhea
• Double vision or blurred vision
• Unsteadiness or difficulty with coordination (ataxia)
• Low sodium levels in the blood (hyponatremia), which can cause headache, nausea, weakness, confusion.

More serious, but less common, side effects can include:

• Severe skin reactions (e.g., Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis)
• Changes in blood cell counts (e.g., decreased white blood cells, leading to increased infections)
• Liver problems
• Mood or behavior changes, including depression and suicidal thoughts.

Precautions and Warnings:

• Blood tests: Your doctor may recommend regular blood tests to monitor sodium levels and blood cell counts.
• Kidney and Liver problems: Use with caution, and dosage adjustments may be necessary.
• Pregnancy and Breastfeeding: Consult your doctor. It may pose risks during pregnancy, and it can pass into breast milk. Effective contraception should be discussed.
• Alcohol: Avoid alcohol as it can increase drowsiness and other side effects.
• Driving and Operating Machinery: Exercise caution as this medication can cause dizziness, drowsiness, and blurred vision.

Manufacturer: Zenoxa-450mg is manufactured by Intas Pharmaceuticals Ltd.

Price in Nepal (as of June 2025): The price for Zenoxa-450mg in Nepal can vary. For a strip of 10 tablets, it might typically range from NPR 250 to NPR 300. However, prices can fluctuate based on the specific pharmacy and current market conditions. Other brands of Oxcarbazepine 450mg are also available in Nepal.

Important Note: This information is for general knowledge and should not be considered medical advice. Always consult a qualified healthcare professional for diagnosis, treatment, and any questions regarding your medical condition or medication.