NOVORAPID PENFIL (100IU/ML)

Description

NOVORAPID PENFIL (100IU/ML) contains Insulin Aspart, which is a rapid-acting insulin analogue. The “100IU/ML” signifies its concentration (100 International Units per milliliter). It comes in a Penfill cartridge, designed to be loaded into a reusable insulin pen device.

Key features and uses:

• Insulin Aspart: This insulin is genetically engineered to act much faster than regular human insulin. Its onset of action is typically within 10-20 minutes, and its effects last for approximately 3-5 hours.
• Mealtime Insulin: Due to its rapid action, NovoRapid is primarily used to control the rise in blood sugar that occurs after meals (post-prandial glucose excursions).
• Treatment of Diabetes Mellitus: It is prescribed for individuals with both Type 1 and Type 2 diabetes mellitus (adults, adolescents, and children aged 1 year and above).
• Often Combined: It’s usually used in conjunction with a longer-acting (basal) insulin or other oral diabetes medications to provide comprehensive blood sugar control throughout the day.
• Prevents Complications: By effectively managing blood sugar spikes, it helps reduce the risk of long-term diabetes complications affecting the kidneys, eyes, nerves, and cardiovascular system.

Administration:

• Penfill Cartridge & Pen Device: The cartridges are designed to be used with specific reusable insulin pen devices (e.g., Novo Nordisk pens like FlexPen). Patients are trained by their healthcare provider on the correct use of the pen.
• Subcutaneous Injection: It is injected under the skin (subcutaneously). Common injection sites include the abdomen, thigh, upper arm, or buttocks. The abdomen generally allows for faster absorption.
• Timing: NovoRapid should be injected within 15 minutes before a meal, or immediately (within 20 minutes) after starting a meal. It’s crucial to consume a meal soon after injection to prevent hypoglycemia.
• Rotation of Injection Sites: Always rotate injection sites within the chosen area to prevent lipodystrophy (thickening or pitting of the skin) and ensure consistent insulin absorption.
• Do NOT Dilute or Mix: Unless specifically instructed by a healthcare professional for a particular protocol (e.g., in a hospital setting), NovoRapid Penfill should not be diluted or mixed with other insulins.
• Not for IV or Pumps (unless specified): While insulin aspart in vials can sometimes be used intravenously under strict medical supervision (e.g., for diabetic ketoacidosis) or in insulin pumps, the Penfill cartridge formulation is primarily for subcutaneous injection with a pen device.

Important Considerations and Side Effects:

• Hypoglycemia (Low Blood Sugar): This is the most common side effect. Because it’s rapid-acting, hypoglycemia can occur quickly if meals are delayed, missed, or if too much insulin is taken. Symptoms include sweating, shakiness, dizziness, confusion, headache, and hunger. Patients must monitor blood sugar regularly and always carry a source of fast-acting sugar (e.g., glucose tablets, fruit juice) to treat low blood sugar.
• Injection Site Reactions: Redness, pain, swelling, itching, or lumps at the injection site are common. Rotating sites helps minimize these.
• Weight Gain: Some weight gain can occur with insulin therapy.
• Allergic Reactions: While rare, severe allergic reactions are possible.
• Alcohol Consumption: Alcohol can significantly affect blood sugar levels and should be consumed with caution or avoided as advised by your doctor.
• Storage: Unopened cartridges must be refrigerated (2°C-8°C). Once opened and in use (inserted into a pen), they can typically be stored at room temperature (below 30°C or 25°C, check the specific product leaflet) for a limited period (e.g., up to 28 days). Do not freeze.
• Pregnancy and Breastfeeding: Generally considered safe if prescribed, but always discuss with your doctor.
• Driving/Operating Machinery: Be cautious if your blood sugar levels are too low or too high, as it can affect your concentration and reaction time.

Always consult your doctor, pharmacist, or diabetes educator for personalized medical advice, proper training on injection technique, and comprehensive management of your diabetes. This information is for general knowledge and should not replace professional medical consultation.