Maxgalin-50mg

Description

“Maxgalin-50mg” refers to a medication that contains Pregabalin 50 mg.

Pregabalin is an anticonvulsant and neuropathic pain agent.

Key Information about Maxgalin-50mg (Pregabalin 50mg):

• Active Ingredient: Pregabalin (50 mg).

• Drug Class: Anticonvulsant (Antiepileptic Drug) and a gabapentinoid.

• Manufacturer: In Nepal and India, Maxgalin is commonly manufactured by Sun Pharmaceutical Industries Ltd.

• Uses (Indications): Maxgalin-50mg is primarily prescribed for:

  • Neuropathic Pain: This is its most common use. It helps relieve pain caused by nerve damage due to various conditions like:
    • Diabetic neuropathy (nerve damage from diabetes)
    • Postherpetic neuralgia (nerve pain after shingles/herpes zoster infection)
    • Spinal cord injury
    • Other forms of chronic nerve pain.
  • Fibromyalgia: A chronic condition characterized by widespread musculoskeletal pain, fatigue, and other symptoms.
  • Generalized Anxiety Disorder (GAD): It can be used to treat symptoms of anxiety, especially when other medications are not suitable.
  • Epilepsy/Seizures: It can be used as an add-on therapy (adjunctive treatment) with other medications to control certain types of seizures (partial-onset seizures).

• How it Works: Pregabalin is believed to work by modulating calcium channel activity in the nervous system. By binding to a specific subunit of voltage-gated calcium channels, it reduces the release of certain excitatory neurotransmitters (chemicals that transmit pain signals) in the brain and spinal cord. This action helps to calm overactive nerves, thereby reducing pain signals and preventing seizures.

• Dosage and Administration:

  • Maxgalin-50mg is an oral capsule and can be taken with or without food.
  • The dosage is highly individualized and determined by a doctor based on the condition being treated, the patient’s response, and kidney function.
  • It’s typically taken once, twice, or three times a day, often with the evening dose being larger or taken at bedtime due to potential drowsiness.
  • Do NOT stop taking this medication suddenly. Abrupt discontinuation can lead to withdrawal symptoms (e.g., headache, insomnia, nausea, anxiety, seizures) and an increase in seizure frequency if used for epilepsy. The dose should be gradually reduced under medical supervision.

• Common Side Effects:

  • Dizziness, drowsiness, sleepiness, fatigue
  • Blurred vision, double vision (diplopia)
  • Weight gain (due to increased appetite and fluid retention)
  • Swelling in hands and feet (peripheral edema)
  • Dry mouth
  • Difficulty concentrating, memory impairment
  • Constipation, nausea, vomiting
  • Headache

• Serious Side Effects (Less Common):

  • Allergic reactions: Hives, blistering, swelling of face/lips/tongue/throat, difficulty breathing. Seek immediate medical attention if these occur.
  • Suicidal thoughts or behavior: Patients should be monitored for any changes in mood, behavior, or the emergence of suicidal ideation.
  • Breathing problems: Can cause slow or shallow breathing, especially in older adults or those with respiratory issues (like COPD).
  • Heart problems: Use with caution in patients with heart conditions like congestive heart failure.
  • Muscle pain, tenderness, or weakness with fever and dark urine (rhabdomyolysis).

• Warnings and Precautions:

  • Prescription Only: Maxgalin-50mg is a prescription medication. Do not use it without consulting a qualified healthcare professional.
  • Driving/Operating Machinery: Avoid these activities until you know how the medication affects you, due to potential dizziness and drowsiness.
  • Alcohol: Avoid alcohol consumption, as it can worsen side effects like dizziness and drowsiness.
  • Kidney Impairment: Dosage adjustments are necessary for patients with kidney disease.
  • Pregnancy and Breastfeeding: Discuss with your doctor. It may cause harm to a developing baby and passes into breast milk.
  • Diabetes: If you have diabetes, monitor your blood sugar levels regularly, as Pregabalin can affect them. Also, report any rapid weight gain or swelling.
  • History of Substance Abuse: Use with caution in patients with a history of drug misuse or dependence.