LOSANORM 25-H

Description

LOSANORM 25-H is a medication primarily used for the treatment of hypertension (high blood pressure). It is a combination medication, meaning it contains two active ingredients that work together to lower blood pressure effectively. This combination is typically prescribed when a single medication isn’t enough to control blood pressure.

The two active ingredients in LOSANORM 25-H are:

1. Losartan (25mg): This belongs to a class of drugs called Angiotensin II Receptor Blockers (ARBs). Losartan works by blocking the action of a natural substance in the body (angiotensin II) that causes blood vessels to narrow. By blocking this action, Losartan helps to relax and widen blood vessels, allowing blood to flow more easily and thereby lowering blood pressure.

2. Hydrochlorothiazide (HCTZ) (12.5mg): This is a thiazide diuretic, often referred to as a “water pill.” Hydrochlorothiazide increases the amount of salt and water that your kidneys remove from your body through urine. This reduces the total fluid volume in the body, which also contributes to lowering blood pressure.

By combining these two mechanisms, LOSANORM 25-H provides a more potent blood pressure-lowering effect than either drug alone. Lowering blood pressure is crucial to reduce the risk of serious cardiovascular complications such as heart attack, stroke, and kidney problems.

Dosage and Administration:

LOSANORM 25-H is typically taken orally once daily, with or without food. It’s often recommended to take it in the morning to avoid frequent urination at night due to the diuretic component. Always follow your doctor’s instructions regarding the precise dosage and duration of treatment. It’s vital not to stop taking this medication suddenly, even if you feel well, as high blood pressure often has no noticeable symptoms, and abrupt discontinuation can lead to a dangerous increase in blood pressure.

Common Side Effects:

• Dizziness (especially when standing up quickly)
• Headache
• Fatigue or weakness
• Nausea, indigestion, diarrhea, or stomach pain
• Cough (though less common than with ACE inhibitors like Ramipril)
• Muscle pain or cramps
• Nasal congestion or sinusitis
• Electrolyte imbalance (e.g., low potassium or sodium levels, high uric acid levels)
• Increased urination

Serious Side Effects (Seek immediate medical attention if you experience):

• Allergic reactions (Angioedema): Swelling of the face, lips, tongue, or throat, which can cause difficulty breathing or swallowing.
• Severe skin reactions (blistering, peeling skin).
• Signs of kidney problems (e.g., producing less urine, swelling in legs/ankles, confusion).
• Signs of liver problems (e.g., yellowing of skin or eyes, dark urine, pale stools, severe stomach pain).
• Very low blood pressure (hypotension), leading to lightheadedness or fainting.
• Signs of high potassium levels (hyperkalemia), such as irregular heartbeat or muscle weakness.
• Eye pain, blurred vision (which could indicate acute angle-closure glaucoma, a serious eye condition).

Important Precautions and Warnings:

• Pregnancy: LOSANORM 25-H is generally unsafe to use during pregnancy, particularly in the second and third trimesters, as it can cause serious harm to the unborn baby. Inform your doctor immediately if you are pregnant or planning a pregnancy.
• Breastfeeding: It is generally not recommended to breastfeed while taking this medication as it may pass into breast milk and harm the baby.
• Kidney Disease: Use with caution in patients with kidney problems. Dose adjustment and regular monitoring of kidney function may be needed. Not recommended for severe kidney impairment or in patients undergoing dialysis.
• Liver Disease: Use with caution in patients with liver problems.
• Diabetes: This medication can affect blood sugar levels and may require dose adjustments for diabetes medications. It should not be used in diabetic patients with impaired kidney function who are also taking Aliskiren (another blood pressure-lowering medicine).
• Dehydration/Electrolyte Imbalance: It’s important to stay hydrated. Your doctor will likely monitor your electrolyte levels, especially potassium and sodium.
• Gout: Hydrochlorothiazide can increase uric acid levels, potentially worsening gout.
• Lupus: May worsen symptoms of systemic lupus erythematosus.
• Alcohol: Avoid alcohol consumption as it can increase dizziness and further lower blood pressure.
• Driving/Operating Machinery: LOSANORM 25-H can cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how you react to the medication.
• Potassium Supplements: Avoid potassium supplements or potassium-rich foods unless specifically advised by your doctor, as this medication can increase potassium levels in the blood.
• Surgery: Inform your doctor or dentist that you are taking LOSANORM 25-H if you are scheduled for any surgery or dental procedure that requires anesthesia.

This information is for general understanding and does not replace professional medical advice. Always consult your doctor or a healthcare professional for diagnosis and treatment specific to your condition.