Lancid

Description

Lancid 30mg Capsule: Your Guide to Lansoprazole

Lancid 30mg Capsule contains Lansoprazole 30mg and is manufactured by Micro Labs Ltd. It’s available in Nepal, typically in a pack of 10 capsules, with a retail price of NPR 9.35. A 15mg capsule strength is also available.

What is Lancid Capsule Used For?

Lancid (Lansoprazole) is a proton pump inhibitor (PPI) that reduces stomach acid production. It’s used to treat various acid-related conditions, including:

• Peptic ulcer (stomach and duodenal ulcers)
• H. pylori infection (in combination therapy)
• Gastro-oesophageal reflux disease (GERD)
• Hypersecretory conditions (e.g., Zollinger-Ellison syndrome)
• Acid-related dyspepsia (indigestion)
• NSAID-induced ulcers (ulcers caused by pain relievers)
• Erosive oesophagitis (inflammation and damage to the esophagus)

How to Take Lancid Capsule

Take Lancid on an empty stomach, preferably before meals. Always follow your doctor’s instructions.

Adult Dosage

• Peptic Ulcer:
  • Duodenal Ulcer: 30 mg once daily in the morning for up to 4 weeks.
  • Gastric Ulcer: 30 mg once daily in the morning for up to 8 weeks.
  • Maintenance: 15 mg once daily.
• Zollinger-Ellison Syndrome (Excessive Acid Production):
  • Initially, 60 mg once daily in the morning. Your doctor will adjust the dose as needed.
  • Daily doses greater than 120 mg should be divided into two doses.
• Acid-Related Dyspepsia (Indigestion):
  • 15-30 mg once daily in the morning for 2-4 weeks.
• Gastro-oesophageal Reflux Disease (GERD):
  • 15-30 mg once daily in the morning for 4-8 weeks.
  • Maintenance: 15-30 mg once daily, adjusted based on your response.
• Prophylaxis of NSAID-induced Ulcers (Prevention):
  • 15-30 mg once daily in the morning.
• H. pylori Infection (Triple Therapy):
  • A 1-week course: 30 mg twice daily (bid) combined with clarithromycin 500 mg twice daily and amoxicillin 1 g twice daily.
  • Alternatively, 30 mg twice daily (bid) combined with clarithromycin 250 mg twice daily and metronidazole 400 mg twice daily.
• Erosive Oesophagitis:
  • 30 mg once daily in the morning for up to 8 weeks. An additional 8 weeks may be needed if healing is not complete.
  • Maintenance: 15 mg once daily.
• NSAID-Associated Ulceration (Treatment):
  • 30 mg once daily in the morning for 4-8 weeks.

Elderly Patients: No dosage adjustment is typically needed.

Hepatic Impairment (Severe Liver Disease): Maximum dose should be 30 mg per day.

Child Dosage

• Gastro-oesophageal Reflux Disease (GERD) & Erosive Oesophagitis:
  • 1-11 years:
    • For children weighing <30 kg: 15 mg once daily in the morning for up to 12 weeks.
    • For children weighing >30 kg: 30 mg once daily in the morning for up to 12 weeks.
    • Doses may be increased up to 30 mg twice daily if symptoms persist after 2 or more weeks of treatment.
  • 12-17 years:
    • GERD: 15 mg once daily for up to 8 weeks.
    • Erosive Oesophagitis: 30 mg once daily for up to 8 weeks.

Renal Impairment (Kidney Disease): No dosage adjustment is needed.

Important Consideration

Do Not Take Lancid if You Have:

• Known hypersensitivity to Lansoprazole or any of its ingredients.

Use With Caution If You Have:

• Hepatic impairment (liver problems).
• Gastric malignancy (stomach cancer) should be ruled out before starting treatment, as Lansoprazole can mask symptoms.
• If you are pregnant or breastfeeding:
  • Pregnancy: Discuss with your doctor.
  • Lactation: It’s unknown if Lansoprazole passes into breast milk; breastfeeding is not recommended during treatment.

Drug Interactions

Inform your doctor about all medications you are taking, including over-the-counter drugs and supplements, to avoid potential interactions.

• Increased Risk of Hypomagnesemia: When taken with diuretics (water pills) and digoxin.
• Decreased Plasma Concentration: May lower the levels of erlotinib, dasatinib, and lapatinib.
• Decreased Bioavailability: May reduce the absorption of itraconazole and ketoconazole.
• Increased Plasma Concentration: May raise the levels of cilostazol and methotrexate.
• Reduced Bioavailability: Effects of Lancid may be reduced by antacids and sucralfate (take Lancid at least 30 minutes before antacids or sucralfate).

Potentially Fatal Interactions:

• May significantly decrease the serum levels and pharmacological effects of rilpivirine and atazanavir (antiviral medications).

Possible Side Effects

Like all medications, Lancid can cause side effects. Contact your doctor if you experience any concerning symptoms.

Common Side Effects (1-10% incidence):

• Headache (3-7%)
• Diarrhea (1-5%)
• Constipation (1-5%)
• Nausea (1-3%)
• Abdominal pain (1-3%)

Less Common Side Effects (<1% incidence):

• Anxiety, angina (chest pain), palpitations, syncope (fainting), edema (swelling), anorexia (loss of appetite), dry mouth, tenesmus (straining during bowel movements), flatulence (gas), melena (dark stools), myalgia (muscle pain), tinnitus (ringing in ears), allergic reactions.

How Lancid Works (Mechanism of Action)

Lansoprazole belongs to a class of drugs called Proton Pump Inhibitors (PPIs). It works by blocking the final step of acid secretion in the stomach. It does this by inhibiting the H+/K+ ATPase enzyme system, also known as the “proton pump,” located in the gastric parietal cells (stomach lining cells). This effectively inhibits both basal (resting) and stimulated acid production.

Disclaimer: This information about Lancid Capsule is for general knowledge and informational purposes only. It is not intended for diagnosis, medical advice, or treatment, and should not be considered a substitute for professional medical judgment. Always consult your physician or another qualified healthcare provider with any questions you may have regarding a medical condition or before starting any new treatment.