₨ NPR
Isovent
Colicspam Tablet: Quick Facts
Colicspam Tablet contains 20mg Dicyclomine + 500mg Paracetamol and is made by Leben Laboratories Pvt Ltd. It’s available in Damak, Koshi Province, Nepal.
What It’s Used For
This tablet is used to relieve abdominal pain and cramping, especially with irritable bowel syndrome (IBS).
How to Use (Adults)
- Take 1 tablet four times daily.
- You can take it with or without food.
- Specific doses for children or those with kidney problems aren’t provided; always ask your doctor.
Who Should Not Use It
Don’t use Colicspam if you’re allergic to its ingredients, if you’re pregnant or breastfeeding, or for children younger than 6 months old.
Important Precautions
Use with caution if you have a history of glaucoma, enlarged prostate, urination problems, high blood pressure, nervous system issues, myasthenia gravis, or liver, heart, thyroid, intestinal, or kidney problems.
Side Effects
Common side effects include dizziness, weakness, dry eyes, blurred vision, dry mouth, and abdominal bloating. Higher doses can lead to more serious effects like decreased sweating or irregular heartbeat.
How It Works
Colicspam works by relaxing the smooth muscles in your gut (Dicyclomine) and relieving pain (Paracetamol).
Disclaimer
This information is for general knowledge only and isn’t a substitute for professional medical advice. Always consult your doctor for diagnosis and treatment.
₨30.00
Ask about productDescription
Isovent Tablet
Misoprostol
200mcg
Square Pharmaceuticals Ltd.
| Pack size | 30’s Pack |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 30.00 NPR |
Indications
Isovent Tablet is used for: NSAID-induced ulcers, Termination of pregnancy, Benign gastric and duodenal ulcers
Adult Dose
NSAID-Induced Ulcer Adult: Benign gastric and duodenal ulceration and NSAID associated ulceration: 800 mcg daily (in 2-4 divided doses) with breakfast or main meals and at bedtime; treatment should be continued for at least 4 weeks and may be continued for up to 8 weeks if required. Prophylaxis of NSAID induced gastric and duodenal ulcer: 200 mcg 2-4 times daily taken with NSAID. If this dose cannot be tolerated, a dose of 100 mcg can be used. Misoprostol should be taken for the duration of NSAID therapy Induction of labor: 100 mcg taken orally. If cervical ripening or active labor does not occur, repeated dose of 100- 200 mcg of oral misoprostol is given every 4 hourly until labor is established (as evidenced by a Bishop score of 7 or more). Maximum number of dose is 6. Termination of pregnancy Day 1: 200 mg of mifepristone PO as a single dose under physician supervision Days 2-3: 800 mcg of misoprostol buccally once as a single dose; must be administered a minimum of 24-hr and a maximum of 48-hr following mifeprostone dose on day 1 Days 7-14 Must return for follow-up visit to confirm complete termination has occurred by medical history, clinical examination, hCG testing, or ultrasonographic scan If complete expulsion has not occurred, but the pregnancy is not ongoing, women may be treated with another dose of misoprostol 800 mcg buccally with follow-up in ~7 days Lack of bleeding following treatment usually indicates failure; however, prolonged or heavy bleeding is not proof of a complete abortion Surgical evacuation is recommended to manage ongoing pregnancies after medical abortion Prevention of postpartum haemorrhage: 600 mcg orally immediately following delivery.
Child Dose
Renal Dose
Renal impairment: Use with caution; peak plasma concentration, half-life, and bioavailability may be increased, but it is not clear whether these increases are of clinical relevance
Administration
Should be taken with food.
Contra Indications
Misoprostol is contraindicated to anyone with a history of allergy to prostaglandins. Women of childbearing potential. Pregnancy and lactation.
Precautions
In case of prevention and treatment of NSAID induced gastric and duodenal ulcer: Misoprostol is contraindicated in women who are pregnant, and should not be used in women of child bearing potential unless the patient requires NSAID therapy. Women of child bearing potential should be told that they must not be pregnant when Misoprostol therapy is initiated and they must use an effective contraception method while taking misoprostol. Conditions where hypotension might precipitate severe complications e.g. cerebrovascular or CV disease. Inflammatory bowel disease. Patients prone to dehydration. Elderly. Renal impairment. Lactation: Drug is rapidly metabolized in mother to misoprostol acid, which is biologically active and is excreted in breast milk; although no published reports of adverse effects of misoprostol in breast-feeding infants exist, caution should be exercised when misoprostol is administered to breastfeeding women
Pregnancy-Lactation
Interactions
May increase effects of oxytocin. Increased risk of misoprostol-induced diarrhoea with magnesium-containing antacids.
Adverse Effects
Side effects of Misoprostol : >10% Diarrhea (14-40%),Abdominal pain (13-20%) 1-10% Headache (2%) Frequency Not Defined Anaphylaxis,Anemia,Cardiac dysrhythmia,Chest pain,Flatulence,Gastrointestinal hemorrhage,Hearing loss,Myocardial infarction,Nausea Rupture of uterus,Thromboembolic disorder
Mechanism of Action
Misoprostol, a synthetic prostaglandin E1 analogue, exerts its antisecretory activity by directly acting on specific prostaglandin receptors found on the surface of gastric parietal cells. It exerts its protective effects on the mucosa by replacing the prostaglandins consumed during prostaglandin-inhibiting therapies e.g. NSAIDs.
Note
Isovent 200mcg Tablet manufactured by Square Pharmaceuticals Ltd.. Its generic name is Misoprostol. Isovent is availble in Nepal. Farmaco Nepal drug index information on Isovent Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.
Additional information
| form | Oral Tablets |
|---|
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