Hybro DS

Description

Hybro DS Tablet

Hybro DS Tablet, containing Hyoscine Butylbromide as its generic name, is an antispasmodic medication produced by National Healthcare Pvt. Ltd. You can find it in Nepal.

Uses (Indications)

Hybro DS is prescribed to relieve spasms and the pain that comes with them in the:

• Gastrointestinal tract (your stomach and intestines)
• Genitourinary tract (your urinary and reproductive organs)
  • This also covers general abdominal pain.

How it Works (Mechanism of Action)

Hyoscine Butylbromide works by blocking specific receptors called muscarinic receptors. This action helps to relax the smooth muscles in your body, particularly reducing excessive movement in your stomach and intestines.

Dosage Information

Adults:

• Oral: For gastrointestinal or genitourinary spasms, take 20 mg four times daily.
• Injection (IM/IV): A 20 mg dose can be given either intramuscularly (into a muscle) or intravenously (into a vein). If needed, this dose can be repeated after 30 minutes.
  • Maximum Daily Dose: Do not take more than 100 mg per day.

Children:

• Oral (6-12 years): Children in this age group should take 10 mg three times daily for gastrointestinal or genitourinary spasms.

Important Considerations

Do Not Use If You Have (Contraindications):

• Narrow-angle glaucoma
• Acute hemorrhage (severe bleeding)
• Paralytic ileus (a type of bowel obstruction)
• Tachycardia (a very fast heart rate) caused by cardiac insufficiency (heart problems)
• Myasthenia gravis (a disorder that causes muscle weakness)

Use with Caution If You Have (Precautions):

• Liver or kidney disease
• Pyloric stenosis (a narrowing at the outlet of your stomach)
• Urinary retention or prostatic hyperplasia (an enlarged prostate)
• Psychosis or seizure disorders
• Ulcerative colitis (an inflammatory bowel disease)
• Coronary artery disease, tachyarrhythmias (fast, irregular heartbeats), heart failure, or hypertension (high blood pressure)
• Special populations: Exercise caution when prescribing to elderly individuals, children, pregnant, or breastfeeding women.

Potential Drug Interactions

• Increased Sedation: Be careful when combining Hybro DS with alcohol or other central nervous system (CNS) depressants, as this can increase sedative effects.
• Reduced Effects: The effectiveness of Hybro DS might be lessened if you’re also taking acetylcholinesterase inhibitors (medications like donepezil, galantamine, rivastigmine, or tacrine, often used for Alzheimer’s disease).
• Potentially Fatal Interaction: The effects of Hybro DS can be significantly enhanced (potentiated) by other anticholinergic drugs and tricyclic antidepressants (TCAs). This interaction can be severe.

Possible Side Effects (Adverse Effects)

Common side effects of Hyoscine Butylbromide include:

• General: Flushing, dizziness, drowsiness, fatigue, headache, memory loss, weakness, tremor, heat intolerance, and decreased sweating.
• Cardiovascular: Postural hypotension (dizziness when standing up), tachycardia (fast heart rate), and fibrillation.
• Skin: Dry skin, redness, increased sensitivity to light, and rash.
• Gastrointestinal: Bloatedness, constipation, dry throat, difficulty swallowing, nausea, vomiting, and dry mouth.
• Urinary: Painful or difficult urination, and urinary retention.
• Ophthalmic (Eye): Impaired accommodation (difficulty focusing), blurred vision, cycloplegia (paralysis of eye muscles), dry eyes, worsening of narrow-angle glaucoma, increased pressure inside the eye, itching, light sensitivity, and pupil dilation.
• Other: Dry nose.

Rare but Serious Side Effects: Psychotic reactions have been reported rarely.

Potentially Fatal Side Effects: In very severe cases, Hybro DS can lead to central nervous system (CNS) depression, coma, and circulatory and respiratory failure.

Disclaimer

This information about Hybro DS Tablet is for general knowledge and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.