Hostyle FORTE

Description

Hostyle FORTE Tablet, with the generic name Hyoscine Butylbromide, is an antispasmodic medication manufactured by Lomus Pharmaceutical Pvt. Ltd. It’s available in Nepal.

Uses (Indications)

Hostyle FORTE is used to relieve spasms and associated pain in the:

• Gastrointestinal tract (stomach and intestines)
• Genitourinary tract (urinary and reproductive organs)
  • This includes conditions like abdominal pain.

How it Works (Mechanism of Action)

Hyoscine Butylbromide works by blocking muscarinic receptors. This action helps to relax smooth muscles and reduce excessive movement in your stomach and intestines.

Dosage Information

Adults:

• Oral: Take 20 mg four times daily for gastrointestinal or genitourinary spasms.
• Injection (IM/IV): 20 mg can be given via intramuscular (IM) or intravenous (IV) injection. This dose can be repeated after 30 minutes if needed.
  • Maximum Daily Dose: Do not exceed 100 mg per day.

Children:

• Oral (6-12 years): Give 10 mg three times daily for gastrointestinal or genitourinary spasms.

Important Considerations

Do Not Use If You Have (Contraindications):

• Narrow-angle glaucoma
• Acute hemorrhage (severe bleeding)
• Paralytic ileus (bowel obstruction)
• Tachycardia (fast heart rate) due to cardiac insufficiency (heart problems)
• Myasthenia gravis (a muscle weakness disorder)

Use with Caution If You Have (Precautions):

• Liver or kidney disease
• Pyloric stenosis (narrowing of the stomach outlet)
• Urinary retention or prostatic hyperplasia (enlarged prostate)
• Psychosis or seizure disorders
• Ulcerative colitis (inflammatory bowel disease)
• Coronary artery disease, tachyarrhythmias (fast irregular heartbeats), heart failure, or hypertension (high blood pressure)
• Special populations: Elderly individuals, children, pregnant, or breastfeeding women.

Potential Drug Interactions

• Increased Sedation: Avoid or use with caution with alcohol or other central nervous system (CNS) depressants as this can increase sedative effects.
• Reduced Effects: Hostyle FORTE’s effects may be reduced if taken with acetylcholinesterase inhibitors (medications like donepezil, galantamine, rivastigmine, tacrine used for Alzheimer’s disease).
• Potentially Fatal Interaction: The effects of Hostyle FORTE can be significantly increased (potentiated) by other anticholinergic drugs and tricyclic antidepressants (TCAs).

Possible Side Effects (Adverse Effects)

Common side effects include:

• General: Flushing, dizziness, drowsiness, fatigue, headache, memory loss, weakness, tremor, heat intolerance, decreased sweating.
• Cardiovascular: Postural hypotension (dizziness upon standing), tachycardia (fast heart rate), fibrillation.
• Skin: Dry skin, redness, increased sensitivity to light, rash.
• Gastrointestinal: Bloatedness, constipation, dry throat, difficulty swallowing, nausea, vomiting, dry mouth.
• Urinary: Painful urination, difficulty urinating, urinary retention.
• Ophthalmic (Eye): Impaired accommodation (difficulty focusing), blurred vision, cycloplegia (paralysis of eye muscles), dry eyes, narrow-angle glaucoma (worsening), increased eye pressure, itching, light sensitivity, pupil dilation.
• Other: Dry nose.

Rare but Serious Side Effects: Psychotic reactions.

Potentially Fatal Side Effects: Severe central nervous system (CNS) depression, coma, circulatory failure, and respiratory failure.

Disclaimer: This information about Hostyle FORTE Tablet is for general knowledge and informational purposes only, and does not constitute medical advice. It is not intended for diagnosis, treatment, or to be a substitute for the professional judgment of a healthcare provider. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treat