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EMPACT 25 TAB

EMPACT 25 TAB is a medication containing Empagliflozin (25 mg), which belongs to the SGLT2 inhibitor class of drugs. It is primarily used in the management of type 2 diabetes mellitus and, in some cases, for heart failure and kidney protection in diabetic patients.

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Description

EMPACT 25 TAB is a medication containing Empagliflozin (25 mg), which belongs to the SGLT2 inhibitor class of drugs. It is primarily used in the management of type 2 diabetes mellitus and, in some cases, for heart failure and kidney protection in diabetic patients.

Key Features:

  • Active Ingredient: Empagliflozin (25 mg)
  • Drug Class: SGLT2 (Sodium-Glucose Cotransporter-2) Inhibitor
  • Mechanism of Action:
  1. Works by blocking SGLT2 proteins in the kidneys, preventing glucose reabsorption.
  2. Causes excess glucose to be excreted in urine, lowering blood sugar levels.
  3. Also promotes mild weight loss and reduces blood pressure.

Uses (Indications):

  1. Type 2 Diabetes Mellitus – Helps control blood sugar levels.
  2. Heart Failure (HFrEF) – Reduces hospitalization risk in adults with heart failure (even without diabetes).
  3. Chronic Kidney Disease (CKD) – Slows kidney damage in diabetic patients.

Dosage & Administration:

  • Standard dose: 1 tablet (25 mg) once daily in the morning, with or without food.
  • Should be taken with adequate water to prevent dehydration.
  • Not recommended for Type 1 Diabetes or Diabetic Ketoacidosis (DKA).

Side Effects:

Common:

  • Increased urination, thirst.
  • Genital yeast infections (thrush) in men & women.
  • Urinary tract infections (UTIs).

Less Common but Serious:

  • Low blood pressure (dizziness, fainting).
  • Ketoacidosis (rare but dangerous – symptoms: nausea, vomiting, abdominal pain, confusion).
  • Necrotizing fasciitis (Fournier’s gangrene – rare but severe genital infection).

Precautions & Warnings:

  • Avoid if allergic to Empagliflozin.
  • Risk of dehydration – Drink enough fluids.
  • Monitor for signs of yeast/UTI infections.
  • Not for use in severe kidney impairment (eGFR <30).
  • May interact with diuretics (increases dehydration risk).

Additional information

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