Dicimox 125

Description

Dicimox 125 Kid Tablet: Uses, Dosage, & Important Information

Dicimox 125 Kid Tablet, which contains Amoxicillin, is an antibiotic primarily used to treat a wide range of bacterial infections in children. “Kid Tablet” suggests it’s formulated for pediatric use, often being a smaller dose or chewable/dispersible. It’s manufactured by MDZ and is available in Nepal.

What is Dicimox 125 Kid Tablet Used For?

Dicimox 125 Kid Tablet is used to treat various bacterial infections, including:

• Pharyngitis (sore throat)
• Acute otitis media (ear infection)
• Acute bacterial sinusitis
• Endocarditis (heart infection prevention/treatment)
• Anthrax
• Chlamydial cervicitis
• Chlamydial urethritis
• Lyme disease
• Dental abscesses
• Salmonellosis
• Typhoid fever
• Acute uncomplicated gonorrhea
• Infections of the Lower Respiratory Tract
• Skin and Skin Structure infections
• Genitourinary Tract infections
• Infections of the Ear, Nose, and Throat

How to Use Dicimox 125 Kid Tablet

Dicimox 125 Kid Tablet can be taken with or without food. Taking it with meals may improve absorption and help reduce stomach discomfort. As a “Kid Tablet,” it might be chewable or designed to be dissolved in a small amount of water.

Adult Dosage

This section provides general Amoxicillin adult dosing. For specific Dicimox 125 Kid Tablet use, particularly for adults, consult a healthcare professional, as this formulation is primarily for children.

• Susceptible infections: 250-500 mg every 8 hours.
• Uncomplicated gonorrhea with probenecid: 3 g as a single dose.
• Dental abscesses: 3 g, repeat once 8 hours later.
• Uncomplicated acute UTI: 3 g, repeat once 10-12 hours later.
• Prophylaxis of endocarditis (prevention): 2 or 3 g as a single dose, 1 hour before a dental procedure.
• Severe or recurrent respiratory tract infections: 3 g twice daily.
• H. pylori infection: 500 mg three times daily, typically combined with either metronidazole or clarithromycin, and a bismuth compound or an antisecretory drug.
• IV/IM Susceptible infections: 500 mg every 8 hours. (Note: This refers to Amoxicillin in general; Dicimox 125 Kid Tablet is an oral tablet).
• Listerial meningitis with other antibiotics: 2 g every 4 hours for 10-14 days. (Note: This refers to Amoxicillin in general; Dicimox 125 Kid Tablet is an oral tablet).

Child Dosage

• Standard dose: 40–45 mg/kg/day, divided and given every 8-12 hours.
• High dose: 80–90 mg/kg/day, with a maximum of 4 g/day, divided and given every 12 hours.
• For penicillin-resistant S. pneumoniae otitis media: 150 mg/kg/day, divided and given every 8 hours.

Renal Dosage

For patients with kidney impairment:

• Creatinine Clearance (CrCl) 10-30 mL/min: 250-500 mg every 12 hours.
• CrCl <10 mL/min: 250-500 mg every 24 hours.
• Patients on hemodialysis: Should receive 250-500 mg every 24 hours, plus an additional dose during and after each dialysis session.

Important Considerations and Warnings

Do Not Use Dicimox 125 Kid Tablet If You Have:

• A known hypersensitivity (allergy) to amoxicillin or other penicillins.

Precautions:

• Kidney (renal) and liver (hepatic) disease: Use with caution.
• Pregnancy and Lactation: Amoxicillin is excreted in breast milk. Use with caution during pregnancy and lactation.
• Infectious mononucleosis: A skin rash is common with amoxicillin in patients with this condition.
• Monitoring: Plasma concentrations of gentamicin should be monitored in patients receiving high doses or prolonged courses, in infants, the elderly, patients with renal impairment, cystic fibrosis, or significant obesity. Auditory and renal functions should also be monitored.

Interactions:

• Oral Contraceptives: May reduce the effectiveness of oral contraceptives.
• Anticoagulants: May increase the effect of anticoagulants (blood thinners).
• Allopurinol: Increased risk of allergic reactions when used with allopurinol.
• Probenecid: Increases and prolongs blood levels of amoxicillin.
• Other antibiotics: Chloramphenicol, macrolides, sulfonamides, and tetracyclines may interfere with the bactericidal effect of amoxicillin.
• Potentially Fatal Interactions:
  • Neuromuscular hypersensitivity.
  • Pseudomembranous colitis.

Possible Side Effects:

• Hyperactivity, agitation, insomnia, dizziness
• Skin rashes: maculopapular rash, exfoliative dermatitis, urticaria (hives), hypersensitivity vasculitis
• Diarrhea, nausea, vomiting
• Blood disorders: anemia, thrombocytopenia (low platelets), leukopenia (low white blood cells), agranulocytosis (severe low white blood cells)

How Dicimox 125 Kid Tablet Works (Mechanism of Action)

Amoxicillin is an aminopenicillin antibiotic. It works by interfering with the final step of peptidoglycan synthesis, a crucial component of the bacterial cell wall. It does this by binding to specific proteins called penicillin-binding proteins (PBPs), which ultimately leads to the breakdown of the bacterial cell wall and bacterial death.

Disclaimer: This information is for general knowledge only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or another qualified healthcare provider with any questions about a medical condition or before starting any new treatment.