Clinmycin Gel

Description

Clinmycin Gel Ointment (Clindamycin 1%)

Clinmycin Gel Ointment contains Clindamycin 1% and is manufactured by Sumy Pharmaceuticals Pvt. Ltd. It comes in a 10g pack size and is available in Nepal, though its retail price isn’t specified.

What It’s Used For (Indications)

Clinmycin Gel Ointment is a topical antibiotic primarily used to treat Acne vulgaris. It is also indicated for other skin conditions such as:

• Erythrasma
• Rosacea
• Periorificial dermatitis
• Folliculitis
• Stasis
• Chronic lymphoedema and familial pemphigus
• Dermal ulcers

Dosage Information

• Adults: For acne, apply a thin layer onto the affected area twice daily.
• Children:
  • Under 12 years old: Safety and efficacy have not been established.
  • Over 12 years old: Apply a thin layer onto the affected area twice daily.

Administration

Apply a thin layer directly onto the affected skin area.

Important Warnings & Precautions

• Contraindications: Do not use if you have a known hypersensitivity to clindamycin.
• Important Notes: This gel is strictly for topical/cutaneous use only. It is not for oral, ophthalmic (eye), or intravaginal use.
• Sun Exposure: Avoid excessive exposure to sunlight and sunlamps. It is recommended to wear sunscreen daily while using this product.
• Pregnancy & Lactation: Excretion in breast milk is unknown; use with caution in breastfeeding mothers.
• Drug Interactions:
  • May enhance the action of neuromuscular blocking agents (e.g., atracurium).
  • May antagonize the effects of parasympathomimetics.
  • May competitively inhibit the effects of other antibiotics such as macrolides, ketolides, streptogramins, linezolid, and chloramphenicol.
  • Can increase coagulation tests (prothrombin time/INR) and/or bleeding when used with vitamin K antagonists (e.g., warfarin, acenocoumarol, fluindione).
• Side Effects:
  • Common (>10%): Dryness (18-23%), Oiliness (1-18%), Erythema (redness, 7-16%), Peeling (7-11%), and Burning/itching (6-11%).
  • Less Common (1-10%): Headache (3%).

How It Works (Mechanism of Action)

Clindamycin inhibits bacterial protein synthesis by reversibly binding to the 50S subunit of bacterial ribosomes. This action blocks the transpeptidation or translocation reactions necessary for protein production in susceptible organisms, thereby stunting their growth and eventually leading to cell death.

Disclaimer: This information regarding Clinmycin Gel Ointment is for general reference only and is not intended for diagnosis, medical advice, or treatment. It should not be considered a substitute for the exercise of professional medical judgment. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or medication.