₨ NPR
Clinace
Clinace Ointment, manufactured by Maruti Pharma Pvt. Ltd., contains Clindamycin 1% W/V as its active ingredient. It comes in a 15g pack size and has a retail price of 110.00 NPR in Nepal.
Clinace Ointment is used for the topical treatment of various skin conditions, including:
- Acne vulgaris
- Erythrasma
- Rosacea
- Periorificial dermatitis
- Folliculitis
- Stasis dermatitis
- Chronic lymphedema
- Familial pemphigus
- Dermal ulcers
₨110.00
Ask about productDescription
Clinace Ointment is contraindicated in patients with a known hypersensitivity to clindamycin.
Precautions
- This product is not for oral, ophthalmic, or intravaginal use.
- Avoid exposure to sunlight and sunlamps while using this ointment. Wear sunscreen daily.
- Lactation: Excretion in breast milk is unknown; use with caution.
Interactions
- May enhance the action of neuromuscular blocking agents (e.g., atracurium).
- May antagonize the effects of parasympathomimetics.
- May competitively inhibit the effects of macrolides, ketolides, streptogramins, linezolid, and chloramphenicol.
- May lead to increased coagulation tests (prothrombin time/INR) and/or bleeding with vitamin K antagonists (e.g., warfarin, acenocoumarol, fluindione).
Adverse Effects
- Common (greater than 10%): Dryness (18-23%), Oiliness (1-18%), Erythema (7-16%), Peeling (7-11%), Burning/itching (6-11%).
- Less Common (1-10%): Headache (3%).
Mechanism of Action
Clindamycin inhibits bacterial protein synthesis by reversibly binding to the 50S subunit of the bacterial ribosome, thereby blocking the transpeptidation or translocation reactions in susceptible organisms. This results in stunted bacterial cell growth.
Additional information
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