Clin Gel

Clin Gel Gel

Generic Name: Clindamycin 1%

Manufacturer: S.R. Drug Laboratories Pvt. Ltd. (Available in Nepal)

Uses

Clin Gel Gel is a topical antibiotic primarily used for the treatment of:

• Acne vulgaris
• Erythrasma
• Rosacea
• Periorificial dermatitis
• Folliculitis
• Stasis dermatitis
• Chronic lymphoedema (lymphaedema)
• Familial pemphigus
• Dermal ulcers

Dosing Information

Clin Gel Gel is for topical/cutaneous use only.

Adult Dosing

• Acne and other indicated conditions (as 1% preparation): Apply a thin layer onto the affected area twice daily.

Child Dosing

• Children under 12 years old: Safety and efficacy have not been established.
• Children over 12 years old: Apply a thin layer onto the affected area twice daily.

Important Considerations

Do Not Use If:

• You have a hypersensitivity (allergy) to clindamycin.

Precautions:

• This gel is not for oral, ophthalmic (eye), or intravaginal use.
• Avoid exposure to sunlight and sunlamps while using this product. It is recommended to wear sunscreen daily.

Pregnancy & Breastfeeding:

• Pregnancy: Use with caution.
• Lactation (Breastfeeding): It is unknown whether the drug is excreted in breast milk; use with caution.

Drug Interactions

• Neuromuscular blocking agents (e.g., atracurium): May enhance their action.
• Parasympathomimetics: May antagonize their effects.
• Macrolides, Ketolides, Streptogramins, Linezolid, and Chloramphenicol: May competitively inhibit their effects.
• Vitamin K antagonists (e.g., warfarin, acenocoumarol, fluindione): May increase coagulation tests (prothrombin time/INR) and/or lead to bleeding.

Possible Side Effects

Very Common (>10% of people):

• Dryness (18-23%)
• Oiliness (1-18%)
• Erythema (redness) (7-16%)
• Peeling (7-11%)
• Burning/itching (6-11%)

Common (1-10% of people):

• Headache (3%)

How Clin Gel Works (Mechanism of Action)

Clindamycin works by inhibiting protein synthesis in susceptible bacteria. It does this by reversibly binding to the 50S subunit of the bacterial ribosome, which blocks the transpeptidation or translocation reactions necessary for protein production. This ultimately stunts the growth of the bacterial cells.

Disclaimer: This information about Clin Gel Gel is for general knowledge and is not intended for diagnosis, medical advice, or treatment. It should not be considered a substitute for the exercise of professional judgment.