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Clicil Gel
Clicil Gel Ointment: Quick Overview
Clicil Gel Ointment contains Clindamycin 1% and is made by Arya Pharma Lab Pvt. Ltd. It comes in a 15g tube and is available in Nepal.
What it’s for & How to Use It
- Uses: Primarily treats Acne vulgaris. Also used for other skin conditions like erythrasma, rosacea, folliculitis, and dermal ulcers.
- Adults & Children (>12 years): Apply a thin layer to the affected area twice daily.
- Children (<12 years): Safety and effectiveness haven’t been established.
- Administration: For topical skin use only. Do not ingest or apply to eyes or internally.
Important Things to Know
- Don’t use if: You’re allergic to clindamycin.
- Sunlight: Avoid sun exposure and sunlamps. Use sunscreen daily.
- Pregnancy/Lactation: Use with caution; it’s unknown if it passes into breast milk.
- Interactions: Can enhance effects of neuromuscular blockers and blood thinners (like warfarin), increasing bleeding risk. May also affect other antibiotics.
- Side Effects: Common side effects include dryness, oiliness, redness (erythema), peeling, and burning/itching at the application site. Headache is less common.
- How it works: It’s an antibiotic that stops bacterial growth by inhibiting protein synthesis.
Description
Clicil Gel Ointment (Clindamycin 1%)
Clicil Gel Ointment contains Clindamycin 1% W/V and is made by Arya Pharma Lab Pvt. Ltd. It comes in a 15g pack size and is available in Nepal, though its retail price isn’t specified.
What It’s Used For (Indications)
Clicil Gel Ointment is a topical antibiotic used to treat various skin conditions, including:
- Acne vulgaris
- Erythrasma
- Rosacea
- Periorificial dermatitis
- Folliculitis
- Stasis
- Chronic lymphoedema
- Familial pemphigus
- Dermal ulcers
Dosage Information
- Adults: For acne, apply a thin layer to the affected area twice daily.
- Children:
- Under 12 years old: The safety and effectiveness of this product haven’t been established.
- Over 12 years old: Apply a thin layer to the affected area twice daily.
Administration
Apply a thin layer to the affected skin area.
Important Warnings & Precautions
- Do not use if: You have a hypersensitivity to clindamycin.
- Important Notes: This ointment is not for oral, ophthalmic (eye), or intravaginal use.
- Sun Exposure: Avoid exposure to direct sunlight and sunlamps. Wear sunscreen daily while using this product.
- Pregnancy & Lactation: It’s unknown if the drug is excreted in breast milk; use with caution if breastfeeding.
- Drug Interactions:
- May enhance the action of neuromuscular blocking agents (e.g., atracurium).
- May antagonize the effects of parasympathomimetics.
- May competitively inhibit the effects of macrolides, ketolides, streptogramins, linezolid, and chloramphenicol (other antibiotics).
- Can increase coagulation tests (prothrombin time/INR) and/or bleeding when used with vitamin K antagonists (e.g., warfarin, acenocoumarol, fluindione).
- Side Effects:
- Common (>10%): Dryness (18-23%), oiliness (1-18%), erythema (redness, 7-16%), peeling (7-11%), and burning/itching (6-11%).
- Less Common (1-10%): Headache (3%).
How It Works (Mechanism of Action)
Clindamycin works by inhibiting protein synthesis in bacteria. It does this by reversibly binding to the 50S subunit of bacterial ribosomes, which blocks the transpeptidation or translocation reactions. This disruption prevents susceptible organisms from growing, effectively stunting their cell growth.
Disclaimer: This information about Clicil Gel Ointment is for general reference only and is not intended as medical advice or a substitute for professional judgment. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or medication.
Additional information
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