₨ NPR
Cefolac
Cefolac Suspension (Cefixime 100mg/30ml)
Cefolac Suspension, manufactured by Macleods Pharmaceuticals Pvt. Ltd., contains Cefixime, an antibiotic available in Nepal for 117.92 NPR. It treats bacterial infections like pneumonia, typhoid fever, sinusitis, tonsillitis, and bronchitis.
Key Details:
- Available Forms: Also comes as 50mg/30ml suspension and 200mg tablets.
- Dosing:
- Adults: Usually 200-400 mg daily. Single 400 mg dose for gonorrhea. Typhoid fever is 20 mg/kg/day, typically for 7-14 days.
- Children: 8 mg/kg/day for most infections; 15-20 mg/kg/day for typhoid fever (max 400 mg/day). Not for infants under 6 months.
- Kidney Issues: Dose reduction is necessary; max 200 mg daily if CrCl < 20 ml/min.
- Administration: Take with or without food; food or milk can help reduce stomach upset.
- Contraindications: Do not use if you’re allergic to cephalosporins.
- Precautions: Use with caution if you have a history of penicillin allergy, kidney failure, GI disease, or are pregnant/breastfeeding.
- Interactions: Can increase probenecid levels and may dangerously increase bleeding risk with blood thinners.
- Side Effects: Diarrhea (16%) is common. Severe side effect: pseudomembranous colitis.
- Mechanism: Cefixime kills bacteria by stopping them from building their cell walls.
Disclaimer: This information is for general knowledge and is not a substitute for professional medical advice. Always consult a healthcare provider.
₨117.92
Ask about productDescription
Cefolac Suspension
Cefixime
100mg/30ml
Macleods Pharmaceuticals Pvt. Ltd.
| Pack size | |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 117.92 NPR |
Available as:
Indications
Cefolac Suspension is used for: Pneumonia, Pharyngitis, Typhoid fever, Susceptible infections , Sinusitis, Otitis media, Tonsillitis, Soft tissue infections, Respiratory tract infections, Acute Exacerbations of Chronic bronchitis, Gonococcal urethritis, Acute bronchitis
Adult Dose
Acute Bronchitis & Acute Exacerbations of Chronic Bronchitis, Otitis Media, Pharyngitis/Tonsillitis, Uncomplicated Urinary Tract Infections Adult: 200 or 400 mg daily as a single dose or in two divided doses Gonorrhea: 400 mg as a single dose. Typhoid fever: 20 mg/kg body weight daily in two divided dose. The usual treatment of is 7 days. This may be continued for up to 14 days according to the severity of infection.
Child Dose
Child: PO 8 mg/kg/day if <50 kg q12–24h For convalescent oral therapy of serious infections, up to 20 mg/kg/day Powder for Suspension & DS Powder for Suspension: Children above 6 months: 8 mg/kg daily in 1-2 divided doses or 6 months-1year: 75 mg daily 1-4 years: 100 mg daily 5-10 years: 200 mg daily Typhoid Fever 15-20 mg/kg/day PO divided q12hr for 7-14 days; not to exceed 400 mg/day <6 months: Safety and efficacy not established
Renal Dose
Renal impairment: Dose reduction is necessary. CrCl (ml/min) <20 Max: 200 mg daily.
Administration
May be taken with or without food. May be taken w/ food or milk to reduce GI discomfort.
Contra Indications
Hypersensitivity to cephalosporin.
Precautions
History of allergy to penicillins; pregnancy, lactation; renal failure; GI disease. Lactation: Unknown whether drug is excreted in milk
Pregnancy-Lactation
Interactions
Increased concentrations with probenecid. Potentially Fatal: May increase prothrombin time with anticoagulants.
Adverse Effects
Side effects of Cefixime : >10% Diarrhea (16%) Frequency Not Defined Abdominal pain,Candidiasis,Dizziness,Dyspepsia,Elevated transaminases,Eosinophilia,Erythema multiforme,Fever,Flatulence,Headache,Increased blood urea nitrogen (BUN),Increased creatinine,Leukopenia,Nausea,Prolonged prothrombin time (PT),Pruritus,Pseudomembranous colitis,Rash,Serum sickness-like reaction,Stevens-Johnson syndrome,Thrombocytopenia,Urticaria,Vaginitis,Vomiting Potentially Fatal: Pseudomembranous colitis.
Mechanism of Action
Cefixime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Note
Cefolac 100mg/30ml Suspension manufactured by Macleods Pharmaceuticals Pvt. Ltd.. Its generic name is Cefixime. Cefolac is availble in Nepal. Farmaco Nepal drug index information on Cefolac Suspension is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.
Additional information
| form | Oral Tablets |
|---|
Reviews
There are no reviews yet.