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Bestdin

Bestdin Lotion (Povidone Iodine 5% Topical): For Skin Infections and Wound Care

Bestdin Lotion, manufactured by Amtech Pharma and available in Nepal, is a topical antiseptic containing Povidone Iodine. It is used for its broad-spectrum germicidal activity to prevent and treat various skin infections.

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Description

Regular use of Bestdin Lotion is contraindicated in:

  • Patients or users with thyroid disorders, particularly nodular colloid goitre, endemic goiter, and Hashimoto’s thyroiditis.
  • Infants under 2 years of age.
  • Patients on concurrent lithium therapy (regular use should be avoided).

Special caution is needed when making regular applications to broken skin in patients with pre-existing renal insufficiency.


Precautions

  • Use with caution during pregnancy and lactation.
  • Use with caution in neonates.
  • Avoid application to large areas of denuded skin or severe burns, as this can lead to systemic absorption and adverse effects.

Pregnancy and Lactation

Use with caution during pregnancy and lactation.


Interactions

Information not explicitly provided for interactions with other medications, but potential systemic absorption should be considered.


Adverse Effects

  • Local side effects: Local skin irritation and sensitivity. Occasionally, mild-transient burning or sticky sensation, and very rarely irritation or hypersensitivity reactions are reported.
  • Systemic effects (due to iodine absorption): Application to large areas of denuded skin, large wounds, or severe burns may produce systemic adverse effects such as:
    • Metabolic acidosis
    • Hypernatremia
    • Impairment of renal function

Mechanism of Action

Povidone-iodine is an iodophore that possesses powerful broad-spectrum germicidal activity. It is effective against a wide range of bacteria, viruses, fungi, protozoa, and spores. Its microbicidal action occurs through the oxidation of cell constituents and the iodination and inactivation of proteins, leading to the destruction of microorganisms.


Other Brands of Povidone Iodine 5% Topical in Nepal

  • Betadine Std Soln 5% (Win-Medicare Pvt. Ltd.)
  • Betadine Powder (Win-Medicare Pvt. Ltd.)
  • Povidone Iodine 5% Cream (Chemi Drug Industries Pvt. Ltd.)
  • Pividine 5% Ointment (Lomus Pharmaceutical Pvt. Ltd.)
  • Pividine 5% Sol (Lomus Pharmaceutical Pvt. Ltd.)

Additional information

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