Alidox 100

Description

Do NOT take Alidox 100 if you have:

• A known allergy to tetracyclines.
• Severe liver problems.
• Systemic lupus erythematosus.

Avoid taking Alidox 100 with:

• Alkalis, antacids, or iron preparations, as they can reduce absorption.
• Penicillin, as it may interfere with penicillin’s effectiveness.

Precautions:

• Tooth Discoloration: Doxycycline can cause permanent tooth discoloration in children up to 12 years old and in the last half of pregnancy. It should only be used in these age groups if other treatments are not effective or are contraindicated.
• Pregnancy & Lactation: Doxycycline is generally not recommended during pregnancy unless deemed essential by a physician. It enters breast milk and is not recommended for breastfeeding mothers.

Drug Interactions:

Be sure to inform your doctor about all medications you are taking, especially:

• Isotretinoin (can cause pseudotumor cerebri).
• Anticoagulants (e.g., warfarin), as it can increase bleeding risk.
• Oral contraceptives (risk of breakthrough bleeding).
• Phenobarbital, carbamazepine, primidone, phenytoin, rifampicin (can decrease doxycycline’s effectiveness).
• Ciclosporin (can increase ciclosporin levels).
• Potentially Fatal Interaction: Avoid concurrent use with methoxyflurane due to the risk of fatal kidney toxicity.

Possible Side Effects

Doxycycline can cause various side effects, including:

• Common: Abdominal pain, nausea, vomiting, diarrhea, indigestion, headache, photosensitivity (increased sensitivity to sunlight).
• Less Common/Serious: Hypotension, pericarditis, angioedema, dyspnea, serum sickness, peripheral edema, tachycardia, urticaria, hemolytic anemia, thrombocytopenia, neutropenia, porphyria, eosinophilia, brown-black microscopic discoloration of thyroid tissue, bulging fontanelles in infants, benign intracranial hypertension in adults, blurred vision, scotomata, diplopia, tinnitus, stomatitis, anorexia, esophageal ulceration, tooth discoloration, enamel hypoplasia, transient increases in liver function tests and BUN, jaundice, pancreatitis, rashes, exfoliative dermatitis, photo-onycholysis, arthralgia, myalgia, vaginitis.
• Potentially Fatal: Anaphylactoid reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, Clostridium difficile-associated disease (CDAD), hepatotoxicity.

How does Alidox 100 work?

Doxycycline works by inhibiting bacterial protein synthesis, preventing bacteria from growing and multiplying. It has a broad spectrum of activity against many types of bacteria.