₨ NPR
Ulfast
Ulfast 150mg Tablet, manufactured by Sun Pharmaceutical Industries Ltd., contains the active ingredient Ranitidine. It’s available in Nepal and is used to treat various conditions related to excess stomach acid.
Key Uses (Indications)
Ulfast Tablet is prescribed for:
- Dyspepsia (indigestion)
- H. pylori infection (in combination with other medications)
- Benign gastric and duodenal ulceration
- Gastro-oesophageal reflux disease (GERD)
- Acid aspiration during general anesthesia (prophylaxis)
Description
Contraindications
- Porphyria
Precautions
- Before starting treatment, your doctor should rule out the possibility of malignancy, as Ranitidine can mask symptoms and delay diagnosis of gastric cancer.
- Use with caution in patients with difficulty swallowing.
- Requires careful consideration in patients with renal and hepatic impairment.
- Pregnancy and lactation: Use with caution. The drug crosses into breast milk; consider discontinuing the drug or using an alternative.
Interactions
- Propantheline bromide can delay absorption and increase peak serum concentration of Ranitidine.
- Ranitidine minimally inhibits the metabolism of coumarin anticoagulants, theophylline, diazepam, and propanolol.
- May alter the absorption of pH-dependent drugs (e.g., ketoconazole, midazolam, glipizide).
- May reduce bioavailability when taken with antacids.
Possible Side Effects
Common (1-10%):
- Headache (3%)
Less Common (<1%):
- Abdominal pain, agitation, alopecia, confusion, constipation, diarrhea, dizziness, hypersensitivity reaction, nausea, vomiting.
Rare (Frequency Not Defined, but potentially serious):
- Anemia, necrotizing enterocolitis (in fetus or newborn), pancreatitis, thrombocytopenia, pancytopenia, agranulocytosis, acquired immune hemolytic anemia, arthralgia, myalgia.
Potentially Fatal:
- Anaphylaxis, severe hypersensitivity reactions.
Mechanism of Action
Ranitidine works by competitively blocking histamine at the H2-receptors located on the gastric parietal cells. This action inhibits the secretion of gastric acid. It does not affect pepsin secretion, pentagastrin-stimulated intrinsic factor secretion, or serum gastrin levels.
Other Brands of Ranitidine in Nepal
- Injection: Umetac 50mg (Umedica)
- Tablets:
- Tagon 150mg (Apex Pharmaceuticals Pvt. Ltd.)
- Acidin 150mg (S.R. Drug Laboratories Pvt. Ltd.)
- Aciloc 150mg (Cadila Pharmaceuticals Limited.)
- Aciloc 300mg (Cadila Pharmaceuticals Limited.)
Additional information
| form | PACK |
|---|
Reviews
There are no reviews yet.