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Description
SENTIPR is an antipsychotic medication containing Olanzapine (5mg), classified as an atypical antipsychotic (second-generation). It is primarily used for managing psychotic disorders, bipolar disorder, and as an adjunct in treatment-resistant depression.
Key Features:
✔ Broad-spectrum efficacy for positive & negative schizophrenia symptoms
✔ Mood-stabilizing properties in bipolar disorder
✔ Long-acting with once-daily dosing
✔ Available as standard oral tablets
Mechanism of Action:
- Dopamine (D2) & Serotonin (5-HT2A) receptor antagonism → reduces psychosis
Additional effects on:
- Muscarinic receptors
- Histamine H1 receptors
- Adrenergic α1 receptors
Therapeutic Uses:
-
Schizophrenia (acute/mantenance phases)
-
Bipolar I Disorder (mania/mixed episodes)
-
Treatment-Resistant Depression (with fluoxetine)
-
Chemotherapy-Induced Nausea (off-label)
Dosage & Administration:
- Initial dose: 5-10mg once daily
- Maintenance: 10-20mg/day (max: 20mg/day)
- Take with/without food (evening doses reduce sedation)
Side Effects:
Common:
- Weight gain
- Sedation
- Dry mouth
- Increased appetite
Additional information
| form | Oral Tablets |
|---|
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