Omnatax

Description

Omnatax Tablet

Generic Name: Cefixime

Manufacturer: Abbott India Ltd. (Available in Nepal)

Uses

Omnatax Tablet is used to treat a variety of susceptible bacterial infections, including:

• Respiratory Tract Infections: Pneumonia, sinusitis, pharyngitis, tonsillitis, acute bronchitis, and acute exacerbations of chronic bronchitis.
• Ear Infections: Otitis media.
• Other Infections: Typhoid fever, soft tissue infections, uncomplicated urinary tract infections, and uncomplicated gonococcal urethritis.

Dosing Information

Omnatax can be taken with or without food. Taking it with food or milk may help reduce gastrointestinal discomfort.

Adult Dosing

• For most infections (acute bronchitis, acute exacerbations of chronic bronchitis, otitis media, pharyngitis/tonsillitis, uncomplicated urinary tract infections): Take 200 mg or 400 mg once daily, or split into two divided doses.
• For gonorrhea: Take a single dose of 400 mg.
• For typhoid fever: Take 20 mg/kg of body weight daily, divided into two doses. Treatment usually lasts 7 days, but your doctor might extend it up to 14 days depending on the severity of your infection.

Child Dosing

• For children weighing less than 50 kg: Give 8 mg/kg daily by mouth, administered either once a day or split into two doses (every 12 to 24 hours).
• For serious infections requiring follow-up oral treatment: Doses can go up to 20 mg/kg daily.

Dosing for Powder for Suspension & DS Powder for Suspension:

• Children above 6 months: 8 mg/kg daily, divided into 1-2 doses.
• 6 months to 1 year: 75 mg daily.
• 1-4 years: 100 mg daily.
• 5-10 years: 200 mg daily.

For Typhoid Fever in Children:

• Give 15-20 mg/kg/day by mouth, divided every 12 hours, for 7-14 days. Do not exceed 400 mg/day.

Important Note: The safety and efficacy of Omnatax have not been established for children younger than 6 months.

Dosing for Kidney Problems

If you have kidney impairment, your doctor will need to adjust your dose.

• Creatinine Clearance (CrCl) less than 20 ml/min: The maximum dose is 200 mg daily.

Important Considerations

Do Not Use If:

• You are allergic to cephalosporin antibiotics.

Use With Caution If You Have:

• A history of allergic reactions to penicillins.
• Renal failure.
• Gastrointestinal disease.

Pregnancy & Breastfeeding:

• Pregnancy: Use with caution.
• Breastfeeding: It is unknown whether Cefixime is excreted in breast milk.

Drug Interactions

• Probenecid: Can increase the concentration of Cefixime in your body.
• Anticoagulants (blood thinners): Omnatax may potentially increase your risk of bleeding by prolonging prothrombin time. This interaction can be serious.

Possible Side Effects

Very Common (>10% of people):

• Diarrhea (16%)

Other Side Effects (Frequency Not Defined):

• Abdominal pain, candidiasis (yeast infection), dizziness, dyspepsia (indigestion), elevated transaminases (liver enzymes), eosinophilia (increased white blood cells), erythema multiforme (a severe skin reaction), fever, flatulence (gas), headache, increased blood urea nitrogen (BUN) and creatinine levels, leukopenia (low white blood cell count), nausea, prolonged prothrombin time (PT), pruritus (itching), pseudomembranous colitis (a serious colon inflammation), rash, serum sickness-like reaction (a severe allergic reaction), Stevens-Johnson syndrome (another severe skin reaction), thrombocytopenia (low platelet count), urticaria (hives), vaginitis (vaginal inflammation), and vomiting.

Potentially Life-Threatening Side Effect:

• Pseudomembranous colitis.

How Omnatax Works

Omnatax (Cefixime) is an antibiotic that works by interfering with the synthesis of the bacterial cell wall. It binds to specific proteins called penicillin-binding proteins (PBPs), which are essential for building and maintaining the cell wall. By inhibiting this process, Cefixime prevents the bacteria from forming a complete cell wall, ultimately leading to bacterial cell death.

Disclaimer: This information about Omnatax Tablet is for general knowledge and is not intended for diagnosis, medical advice, or treatment. It should not be considered a substitute for professional medical judgment.