₨ NPR
Motilium
Motilium M 10mg Tablet is a medication primarily used to relieve symptoms like nausea and vomiting. It contains Domperidone as its active ingredient, a peripheral dopamine-receptor blocker that helps facilitate gastric emptying and improve digestive tract movement. It comes in a pack size of 10 tablets and has a retail price of 4.16 NPR.
Key Uses
Motilium M is indicated for various conditions, including:
- Nausea and vomiting
- Gastritis
- Gastroparesis (slow stomach emptying)
- Non-ulcer dyspepsia (indigestion not caused by ulcers)
- Migraine (for associated nausea/vomiting)
- Lactation (to promote milk production, though this is an off-label use and should be discussed with a doctor)
₨4.16
Ask about productDescription
Contraindications: Do not use Motilium M if you have:
- Hypersensitivity to domperidone.
- Gastrointestinal hemorrhage, obstruction, or perforation.
- A prolactin-releasing pituitary hormone condition.
- It’s generally not for chronic administration or routine prevention of post-operative nausea and vomiting.
Precautions: Use with caution if you have:
- Phaeochromocytoma (a tumor of the adrenal gland).
- Are under 2 years old (children).
- Are elderly.
- Have renal or hepatic impairment.
- There’s a risk of cardiac arrhythmias and hypokalemia (low potassium) if administered intravenously.
- Pregnancy and lactation: Consult your doctor.
Potential Interactions:
- May reduce the effect of bromocriptine (used for high prolactin levels).
- May lessen the prokinetic effect of opioid analgesics and antimuscarinics.
- Potentially Fatal: Taking Motilium M with potent CYP3A4 inhibitors (like ketoconazole, erythromycin, or ritonavir) can significantly increase domperidone levels, raising the risk of serious heart rhythm problems (QT prolongation).
Possible Side Effects:
- Drowsiness, extrapyramidal reactions (movement disorders).
- Galactorrhoea (milk production not related to childbirth), gynecomastia (breast enlargement in males).
- Constipation or diarrhea, lassitude (lack of energy), decreased libido, skin rash, itching.
- Potentially Fatal: In rare cases, seizures, arrhythmias, cardiac arrest, or hypertensive crisis (in patients with phaeochromocytoma) have been reported.
Additional information
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