Klarion 250

Description

Klarion 250 Tablet is prescribed to treat a variety of bacterial infections. These include:

• Respiratory tract infections: Such as pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, and pneumonia (including community-acquired pneumonia and legionellosis).
• Skin and soft tissue infections.
• Leprosy.
• Peptic ulcer disease: Particularly when caused by Helicobacter pylori. It’s often used as part of a multi-drug treatment plan to eradicate the bacteria.
• Lyme disease.
• Acne.

How Do You Take It?

The exact dosage and duration of treatment will be determined by your doctor based on the specific infection, its severity, and your individual response. Always follow your doctor’s instructions carefully.

Adult Dosing (Oral)

• Acute Exacerbation of Chronic Bronchitis: Typically 250-500 mg by mouth every 12 hours for 7-14 days. An extended-release (XL) form might be 1000 mg once daily for 7 days.
• Mycobacterial Infection (Prophylaxis and Treatment): Usually 500 mg by mouth every 12 hours for 7-14 days, often in combination with other anti-mycobacterial drugs such as rifampin and ethambutol.
• Peptic Ulcer Disease: 500 mg by mouth every 8-12 hours for 10-14 days. This is given as part of a 2- or 3-drug combination regimen (e.g., with bismuth subsalicylate, amoxicillin, an H2 receptor antagonist, or a proton pump inhibitor).
• Pharyngitis, Tonsillitis: 250 mg by mouth every 12 hours for 10 days.
• Community-Acquired Pneumonia, Skin/Skin Structure Infection: 250 mg by mouth every 12 hours for 7-14 days. The extended-release form might be 1000 mg once daily for 7 days.
• Endocarditis Prophylaxis: 500 mg by mouth 30-60 minutes before a surgical procedure.

Adult Dosing (Intravenous – for injectable forms, not Klarion 250 Tablet)

• For susceptible infections, 500 mg twice a day for 2-5 days. This is infused over 60 minutes using a 0.2% solution. Revert to oral therapy whenever possible. (Note: Klarion 250 is a tablet, so this section applies to injectable clarithromycin products.)

Adult Dosing (Topical – for topical forms, not Klarion 250 Tablet)

• Apply a thin layer to the affected area once daily. (Note: Klarion 250 is a tablet, so this section applies to topical clarithromycin products.)

Child Dosing (Oral)

• 15 mg/kg per day, with a maximum of 1 gram per day, given every 12 hours.

Renal Impairment

• If your creatinine clearance (CrCl) is less than 30 ml/min, your dosage may need to be halved or the dosing interval doubled.