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Description
GRAND-MD TAB is a combination medication primarily used for the treatment of type 2 diabetes mellitus. It contains two active ingredients that work together to control blood sugar levels:
Composition:
Each tablet typically contains:
- Metformin (500 mg/850 mg/1000 mg) – Biguanide class
- Dapagliflozin (5 mg/10 mg) – SGLT2 inhibitor class
Mechanism of Action:
-
Metformin:
- Reduces glucose production in liver
- Improves insulin sensitivity
- Decreases intestinal glucose absorption
-
Dapagliflozin:
- Blocks SGLT2 receptors in kidneys
- Increases glucose excretion through urine
- Promotes weight loss and lowers blood pressure
Indications:
- Management of type 2 diabetes mellitus in adults
- May be prescribed when single-agent therapy is insufficient
- Particularly beneficial for patients needing:
- Weight management
- Cardiovascular risk reduction
- Kidney protection
Dosage:
- Standard dose: 1 tablet once daily (usually morning)
- Metformin component: Dose adjusted based on individual tolerance (500-2000 mg/day)
- Dapagliflozin component: Fixed at 5 mg or 10 mg
- Should be taken with meals to reduce GI side effects
Side Effects:
Common:
- Gastrointestinal issues (nausea, diarrhea – mainly from metformin)
- Increased urination (from dapagliflozin)
- Genital yeast infections
- Urinary tract infections
Additional information
| form | Oral Tablets |
|---|
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