Glintra

Description

Glintra Gel is a topical medication used to treat mild to moderate inflammatory acne vulgaris and non-inflammatory acne. It can be used alone or with other anti-acne products. It’s particularly effective for acne where comedones (blackheads/whiteheads), papules (small red bumps), and pustules (pus-filled bumps) are the main types of lesions.

Dosage & How to Use

Adult Dose:

• Apply a thin film of the gel to the affected area of the skin once daily in the evening, before going to bed.

Child Dose:

• The safety and effectiveness of Glintra Gel in children under 12 years of age have not been established.

Application Instructions:

1. Cleanse your skin with a mild soap or a soap-free cleanser.
2. Rinse your skin with water.
3. Apply a small amount of gel with clean fingers and gently rub it into the skin.
4. Use just enough gel to lightly cover the entire affected area.

Important Considerations

• Contraindications: Do not use Glintra Gel if you have a history of:
  • Hypersensitivity (allergy) to clindamycin, lincomycin, or adapalene.
  • Regional enteritis (a type of inflammatory bowel disease).
  • Ulcerative colitis.
  • Antibiotic-associated colitis.
• Precautions:
  • Clindamycin Absorption: Even when applied topically, clindamycin can be absorbed into the bloodstream. Cases of diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with both topical and systemic clindamycin. These gastrointestinal issues can sometimes appear several weeks after stopping oral or injected clindamycin.
  • Adapalene Use:
    • Avoid applying the gel to areas with cuts, scrapes, sunburned skin, or eczema.
    • Avoid contact with your eyes, mouth, angles of the nose, and other very sensitive body areas. If accidental contact occurs, wash immediately with warm water.
    • Sun Sensitivity: Limit exposure to strong sunlight and artificial UV light (like tanning beds). It’s recommended to use sunscreen products and wear protective clothing over treated areas.
• Lactation (Breastfeeding): It’s unknown if the active ingredients are excreted in breast milk. Use with caution if breastfeeding.
• Drug Interactions:
  • Clindamycin: Has neuromuscular blocking properties. Use with caution if you are also taking other neuromuscular blocking agents, as clindamycin may enhance their effects.
  • Adapalene: There are no known interactions with other topical medications. However, avoid using other retinoids or drugs with a similar mechanism of action concurrently with adapalene to prevent excessive skin irritation.
• Adverse Effects (Side Effects):
  • Local Effects (Common): Burning, itching, dryness, redness (erythema), and peeling at the application site.
  • Systemic Effects (Rare with Topical Clindamycin but reported): Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis). Abdominal pain and gastrointestinal disturbances, as well as gram-negative folliculitis, have also been reported.
  • Adapalene-Specific Side Effects:
    • Common (may affect up to 1 in 10 people): Dry skin, skin irritation, burning sensation, redness (erythema).
    • Uncommon (may affect up to 1 in 100 people): Local skin reaction (contact dermatitis), skin discomfort, sunburn, itching (pruritus), peeling skin (exfoliation), and flare-up of acne.