Fucidin

Description

Fucidin Ointment (Sodium Fusidate 2% Topical)

Manufacturer: Sun Pharmaceutical Industries Ltd. Generic Name: Sodium Fusidate 2% Topical Availability: Available in Nepal

Indications: Fucidin Ointment is indicated for the treatment of skin infections caused by Staphylococci, Streptococci, Corynebacterium minutissimum, and other fusidic acid-sensitive organisms. The most important indications include:

• Impetigo
• Boils
• Abscess
• Varicose ulcers
• Skin grafts
• Hidradenitis
• Infected wounds
• Sycosis barbae
• Paronychia
• Folliculitis
• Carbuncles
• Erythrasma

Dosage:

Adult Topical/Cutaneous Dose:

• Skin infections: Apply a 2% ointment/cream/gel onto the affected area 3-4 times daily until improvement is observed. If a gauze dressing is used, the frequency of application may be reduced to 1-2 times daily.

Child Topical/Cutaneous Dose:

• Skin infections: Apply a 2% ointment/cream/gel onto the affected area 3-4 times daily until improvement is observed. If a gauze dressing is used, the frequency of application may be reduced to 1-2 times daily.

Renal Dose:

• No specific renal dose adjustment information provided.

Administration: Topical/Cutaneous application.

Contraindications:

• Known hypersensitivity to Fusidic acid.
• Severe hepatic failure.

Precautions:

• Prolonged treatment should be avoided.
• Use with caution in patients with liver impairment.
• Pregnancy: Use with caution.
• Caution should be observed when applying Fucidin Ointment near the eye region, as this preparation may cause irritation if it gets into the eye.

Pregnancy-Lactation:

• Pregnancy: Use with caution.
• Lactation: No specific information provided regarding use during lactation in the given text.

Interactions:

• Synergistic action: With antistaphylococcal penicillin.
• Antagonism: With ciprofloxacin.

Adverse Effects:

• Fucidin Ointment is remarkably well tolerated, with an extremely low frequency of hypersensitivity reactions.
• Rashes and irritation may occur.

Mechanism of Action: Fusidic acid disrupts the translocation of peptide subunits and elongates the peptide chain of susceptible bacteria, thereby inhibiting protein synthesis.

Note: Farmaco Nepal drug index information on Fucidin Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.