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Eudyna

Eudyna Cream, containing Tretinoin Topical, is manufactured by Zydus Pharmaceuticals and is available in Nepal. Tretinoin, a form of vitamin A, works by boosting the turnover of skin cells. This helps to expel existing clogged pores (comedones) and stops new ones from forming. It also thins the outermost layer of the skin.

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Description

This cream is used to treat:

  • Acne
  • Mottled hyperpigmentation (dark spots)
  • Roughness and fine wrinkles on skin damaged by sun exposure

 

How to Use

 

For Adults:

  • Acne vulgaris: Apply once daily, typically at bedtime, to the affected area after you’ve cleansed and dried your skin. You might start seeing results after 6-8 weeks.
  • Mottled hyperpigmentation, roughness, and fine wrinkling of photodamaged skin: Apply a pea-sized amount to your entire face once daily at night. It could take up to 6 months to see a therapeutic response.

For Children:

  • Acne Vulgaris: For children under 12 years, its safety and effectiveness haven’t been established. For those over 12 years, apply once daily at bedtime to the affected area.

 

Important Precautions

 

  • Do not use if you are hypersensitive to retinoids, or if your skin is eczematous (inflamed), sunburnt, or has open wounds.
  • Avoid using if you are pregnant or breastfeeding.
  • Limit your exposure to sunlight, UV light, and extreme weather (like cold).
  • Keep the cream away from your eyes, mouth, corners of your nose, mucous membranes, or open wounds.
  • If you experience severe local redness, swelling, blistering, or crusting, use the cream less frequently or stop using it altogether.
  • Avoid medicated or drying soaps, abrasive soaps and cleansers, frequent washing, and harsh scrubbing.
  • Do not use topical preparations with high concentrations of alcohol, menthol, spices, or lime.

 

Potential Side Effects

 

You might experience an initial worsening of symptoms, skin irritation, stinging when applied, swelling, blistering, crusting of the skin, redness, scaling, increased sensitivity to light (photosensitivity), and temporary lighter or darker skin patches.

 

Drug Interactions

 

Be aware that Tretinoin Topical can:

  • Increase the absorption of minoxidil.
  • Increase the risk of serious blood clots if used with antifibrinolytic medications.
  • Lead to higher tretinoin concentrations when used with azole antifungals.
  • Enhance the peeling action of sulfur, resorcinol, benzoyl peroxide, and salicylic acid.
  • Increase photosensitivity when used with other photosensitizing medications like thiazides, tetracyclines, fluoroquinolones, phenothiazines, and sulfonamides.
  • Potentially cause a fatal increase in pressure inside the skull when combined with tetracyclines.

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