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Dyspam

  • Gastrointestinal tract spasm: General abdominal pain and cramps.
  • Irritable Bowel Syndrome (IBS): Helps manage the spasmodic pain and discomfort commonly experienced with IBS.
  • Dysmenorrhea: Effectively reduces severe menstrual cramps.
  • Biliary colics: Pain arising from spasms in the bile ducts, often associated with gallstones.
  • Renal colics: Intense pain resulting from spasms in the urinary tract, frequently due to kidney stones.

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Description


Dyspam Tablet: Targeted Relief for Spasms

Dyspam Tablet, manufactured by CTL Pharmaceuticals Pvt. Ltd., contains 40mg of Drotaverine Hydrochloride. This medication is an antispasmodic, specifically designed to relieve pain and discomfort caused by involuntary contractions (spasms) of smooth muscles within the body. Dyspam is available in Nepal at a retail price of 3.00 NPR per tablet.

Drotaverine Hydrochloride exerts its antispasmodic effect by directly acting on smooth muscle cells. Its primary mechanism of action involves the inhibition of phosphodiesterase-IV (PDE4), an enzyme found in smooth muscle. By blocking PDE4, Drotaverine increases the intracellular levels of cyclic AMP (cAMP). This elevated cAMP concentration leads to the relaxation of smooth muscles, thereby alleviating the painful spasms and helping to restore normal function. This direct action provides rapid relief without the significant anticholinergic side effects often associated with other antispasmodics.


Dosage Information:

Important: Always follow your doctor’s prescribed dosage and instructions.

  • Adults (Oral): For its antispasmodic effect, the usual adult dose is 1 to 2 tablets (40mg to 80mg), taken 3 times daily.
  • Children (Oral):
    • Children over 6 years: 1/2 to 1 tablet (20mg-40mg), 1-2 times daily.
    • Children 1-6 years: 1/4 to 1/2 tablet (10mg-20mg), 1-2 times daily.
  • Administration: Dyspam Tablet can be taken with or without food.

(Note: The provided information also lists injection dosages, but as this entry is specifically for “Dyspam Tablet,” those are for general Drotaverine use and not directly for this specific tablet product.)


Important Considerations:

  • Contraindications: Do not use Dyspam if you have severe kidney, liver, or heart dysfunction, or if you are diagnosed with porphyria.
  • Precautions: Exercise caution and inform your doctor if you have existing renal, hepatic, or cardiac dysfunction. It should be used cautiously during pregnancy and lactation; consult your doctor.
  • Drug Interactions: Drotaverine may attenuate (weaken) the action of levodopa, a medication used for Parkinson’s disease. It can have an additive beneficial effect when used concurrently with analgesics (pain relievers), antimuscarinics, or benzodiazepines. Always inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, you are currently taking.
  • Adverse Effects (Side Effects): Common side effects of Drotaverine Hydrochloride include vertigo (dizziness), nausea, vomiting, and dry mouth. If these side effects persist, worsen, or if you experience any other concerning symptoms, seek medical advice promptly.

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