Clovate S

Clovate S Cream

Overview: Clovate S Cream contains Salicylic acid, a topical medication that helps to soften and remove the outer layers of the skin. It also possesses mild antiseptic properties. The product label indicates it contains “3%W/W +0.05%W/W,” suggesting two active ingredients, with Salicylic acid being 3% and another ingredient at 0.05% (often a corticosteroid like Clobetasol when “Clovate” is in the name, though the second ingredient’s name is not explicitly provided in your text). This summary focuses on the properties of Salicylic acid as described in the mechanism of action.

Indications: Clovate S Cream is used for the topical treatment of:

• Acne: To help clear existing breakouts and prevent new ones.
• Hyperkeratotic and Scaling Skin Conditions: These are skin conditions characterized by excessive thickening and flaking of the skin (e.g., certain forms of psoriasis, eczema, or dandruff).

Dosage and Administration

Adults:

• Acne: Apply a thin layer of the cream to the affected skin area 1 to 3 times daily. If you experience dryness or peeling of the skin, reduce the application frequency to once daily or every other day.
• Hyperkeratotic and Scaling Skin Conditions: Apply the cream to the affected area of the skin and/or scalp 3 to 4 times daily.

Children:

• Specific dosage information for children is not provided in the original text. Please consult a healthcare professional.

Renal Dose:

• As this is a topical cream, specific dosage adjustments for kidney impairment are generally not necessary unless there is extensive application leading to significant systemic absorption, which is uncommon for Salicylic acid at these concentrations.

Administration:

• Clovate S Cream is strictly for topical (external) use on the skin.

Important Considerations

Contraindications:

• Hypersensitivity: Do not use this cream if you have a known allergy to Salicylic acid or any other ingredients in Clovate S Cream.
• Specific Skin Lesions: Do not apply the cream on moles, birthmarks, unusual warts with growing hair, or warts located on the face.

Precautions:

• Limited Use: This cream is not intended for prolonged use, for application in high concentrations, or for use over large areas of the body.
• Medical Conditions: Use with caution if you have impaired peripheral circulation or diabetes.
• Avoid Sensitive Areas: Be careful to avoid contact with broken skin, the mouth, eyes, mucous membranes (e.g., inside the nose or genitals), and the anogenital region.

Pregnancy and Lactation:

• Information regarding the use of Clovate S Cream during pregnancy and lactation is not provided in the original text. If you are pregnant or breastfeeding, please consult with a doctor or pharmacist before using this product.

Drug Interactions:

• Other Topical Acne Preparations: Using Clovate S Cream alongside other topical acne treatments may increase the risk of skin dryness and irritation.

Adverse Effects (Side Effects):

• Common: Skin irritation, sensitivity, and excessive drying.
• Systemic Effects: While less common with topical use, systemic effects may occur with prolonged use or if applied over very large areas of the body.

Mechanism of Action: Salicylic acid exhibits a powerful keratolytic action when applied topically. This means it helps to soften and shed the outermost layer of the skin (the stratum corneum). It achieves this by increasing the skin’s natural hydration, causing the hardened skin layer to swell, soften, and then peel off. At higher concentrations, salicylic acid can have a caustic (tissue-destroying) effect. Additionally, it possesses mild antifungal and antibacterial properties.

Note: Clovate S 3%W/W + 0.05%W/W Cream is manufactured by CTL Pharmaceuticals Pvt. Ltd. Its generic name is Salicylic acid 2% Topical (though the listed product strength for Salicylic acid is 3%W/W). Clovate S is available in Nepal. This information, provided by Farmaco Nepal drug index, is for general reference and is not intended for diagnosis, medical advice, or treatment. It should not be considered a substitute for the professional judgment of a healthcare provider. Always consult a qualified medical professional for specific health concerns or before starting any new medication.