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Clariwin

Clariwin Tablet is an antibiotic manufactured by Micro Labs Ltd. in Nepal. It contains Clarithromycin 250mg as its active ingredient. This medication is also available in a 500mg tablet strength.

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Description

Clariwin Tablet is prescribed to treat various bacterial infections, including:

  • Respiratory Tract Infections: This covers conditions like pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, and different types of pneumonia (including community-acquired pneumonia and legionellosis).
  • Skin and Soft Tissue Infections.
  • Leprosy.
  • Peptic Ulcer Disease: Particularly when caused by Helicobacter pylori. It’s typically used as part of a multi-drug treatment plan.
  • Lyme Disease.
  • Acne.

 

How Do You Take It?

 

Your doctor will determine the correct dosage based on your infection and age. Always follow their instructions precisely.

 

Adult Dosing (Oral)

 

  • Acute Exacerbation of Chronic Bronchitis: Take 250-500 mg by mouth every 12 hours for 7-14 days. An extended-release form might be 1000 mg once daily for 7 days.
  • Mycobacterial Infection (Prophylaxis and Treatment): Typically 500 mg by mouth every 12 hours for 7-14 days, often in combination with other anti-mycobacterial drugs like rifampin and ethambutol.
  • Peptic Ulcer Disease: 500 mg by mouth every 8-12 hours for 10-14 days. This is administered as part of a 2- or 3-drug combination regimen (e.g., with bismuth subsalicylate, amoxicillin, an H2 receptor antagonist, or a proton pump inhibitor).
  • Pharyngitis, Tonsillitis: 250 mg by mouth every 12 hours for 10 days.
  • Community-Acquired Pneumonia, Skin/Skin Structure Infection: 250 mg by mouth every 12 hours for 7-14 days. The extended-release form might be 1000 mg once daily for 7 days.
  • Endocarditis Prophylaxis: 500 mg by mouth 30-60 minutes before a surgical procedure.

 

Adult Dosing (Intravenous)

 

  • Respiratory Tract Infections; Skin and Soft Tissue Infections; Susceptible Infections: 500 mg twice a day for 2-5 days, infused over 60 minutes using a 0.2% solution. Your doctor will switch you to oral therapy as soon as possible.

 

Adult Dosing (Topical)

 

  • Apply a thin layer to the affected area once daily.

 

Child Dosing (Oral)

 

  • 15 mg/kg per day, with a maximum of 1 gram per day, given every 12 hours.

 

Renal Impairment

 

  • If your creatinine clearance (CrCl) is less than 30 ml/min, your dosage may be halved, or the dosing interval doubled.

 

Administration

 

  • Standard release tablets and oral suspension: You can take these with or without food.
  • Extended-release (XL) and modified-release (MR) tablets: These must be taken with food. Swallow them whole; do not chew or crush them.

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