Betatime

Description

Betatime Topical: Clinical Information

Betatime Topical, containing Povidone Iodine 5% Topical, is indicated for:

• Treatment of primary or secondary topical infections, including infected surgical incisions, decubitus or stasis ulcers, pyodermas, secondarily infected dermatoses, and infected traumatic lesions.
• Prevention of infections in cuts, abrasions, and wounds.

Dosage and Administration (Adults)

• As Ointment:
  • For the treatment of infection: Apply once or twice daily, or at dressing changes, for a maximum of 14 days.
  • For the prevention of infection: Apply once or twice a week for as long as necessary.
  • Apply the ointment directly to the affected area after being cleaned and dried. The treated area may be covered with a dressing or bandage.
• As Powder: Apply as often as required. May be covered with a dressing or bandage.

(Please note: The provided dosage information specifically mentions “Ointment” and “Powder” for a product listed as “Topical,” which could imply various forms. It is crucial to follow the specific instructions for the precise topical form of Betatime if available, or consult a healthcare professional for clarification.)

Contraindications

Regular use of Betatime Topical is contraindicated in:

• Patients with thyroid disorders (specifically nodular colloid goitre, endemic goitre, and Hashimoto’s thyroiditis).
• Infants under 2 years of age.
• Special caution is needed when regular applications to broken skin are made to patients with pre-existing renal insufficiency.
• Regular use should be avoided in patients on concurrent lithium therapy.

Precautions

• Use with caution during pregnancy and lactation.
• Exercise caution when used in neonates.

Adverse Effects

Side effects of Povidone Iodine 5% Topical can include:

• Local skin irritation and sensitivity.
• Application to large areas of denuded skin may lead to systemic effects due to iodine absorption.
• The application of povidone iodine to large wounds or severe burns may produce systemic adverse effects such as metabolic acidosis, hypernatraemia, and impairment of renal function.
• Occasionally, mild-transient burning or sticky sensation.
• Very rarely, irritation or hypersensitivity reactions are reported.

Mechanism of Action

Povidone-iodine is an iodophore that exhibits powerful broad-spectrum germicidal activity against a wide range of bacteria, viruses, fungi, protozoa, and spores. Its microbicidal action occurs by oxidizing cell constituents, iodinating proteins, and subsequently inactivating them.

Note: Betatime 5% Topical is manufactured by Time Pharmaceuticals Pvt. Ltd. Its generic name is Povidone Iodine 5% Topical. Betatime is available in Nepal. This information from the Farmaco Nepal drug index is not intended for diagnosis, medical advice, or treatment; neither is it a substitute for the exercise of professional judgment.