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ADEFOVIR-10MG(AEDSERA)

ADEFOVIR-10MG (AEDSERA) is an oral antiviral medication used in the treatment of chronic hepatitis B virus (HBV) infection. It contains Adefovir Dipivoxil, a nucleotide analog that inhibits the replication of HBV by interfering with the viral DNA polymerase enzyme. This action helps to reduce the viral load in the body, thereby slowing the progression of liver damage associated with chronic HBV infection.

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Description

ADEFOVIR-10MG (AEDSERA) is an oral antiviral medication used in the treatment of chronic hepatitis B virus (HBV) infection. It contains Adefovir Dipivoxil, a nucleotide analog that inhibits the replication of HBV by interfering with the viral DNA polymerase enzyme. This action helps to reduce the viral load in the body, thereby slowing the progression of liver damage associated with chronic HBV infection.

Indication:

  • Treatment of chronic hepatitis B in adults and children aged 12 years and older with evidence of active viral replication and persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.

Dosage:

  • The recommended dose is 10 mg orally once daily, with or without food.

Renal Impairment Adjustments:

  • For patients with creatinine clearance (CrCl) between 30–49 mL/min, the dose is adjusted to 10 mg every 48 hours.

Side Effects:

  • Common side effects include headache, nausea, and diarrhea. Serious side effects may involve liver problems, kidney issues, and lactic acidosis.

Precautions:

  • Not recommended for use in children under 12 years of age.
  • Monitor renal function regularly during treatment.

Additional information

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Oral Tablets

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