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Adapt


 

Adapt Gel: Adapalene 0.1% + Benzoyl Peroxide 2.5%

 

Adapt Gel is a topical medication by Medo Pharma, available in Nepal, combining 0.1% Adapalene and 2.5% Benzoyl Peroxide for acne treatment.

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Description

 

Adapt Gel: Adapalene 0.1% + Benzoyl Peroxide 2.5%

 

Adapt Gel is a topical medication containing 0.1% Adapalene and 2.5% Benzoyl Peroxide. It’s manufactured by Medo Pharma and is available in Nepal.

 

Uses (Indications)

 

Adapt Gel is primarily used for treating acne.

 

How to Use (Administration & Dosage)

 

  • Adults: After washing, apply a thin film of the gel to affected areas of the face and/or trunk once daily. Use a pea-sized amount for each area of the face (e.g., forehead, chin, each cheek).
  • Children (over 9 years): Apply a thin film to affected facial areas and/or trunk once daily in the evening after washing.
  • Children (under 9 years): The safety and effectiveness of Adapt Gel have not been established for this age group.

Important: Avoid contact with your eyes, lips, and mucous membranes.

 

Important Considerations

 

  • Do Not Use If (Contraindications): Do not use Adapt Gel if you are hypersensitive to Adapalene, Benzoyl Peroxide, or any other component of the gel.
  • Precautions:
    • Sun Sensitivity: Minimize exposure to sunlight (including sunlamps) while using this gel. If sun exposure is unavoidable, use sunscreen products and protective apparel (like a hat). Be especially cautious if you have high levels of sun exposure or inherent sun sensitivity.
    • Weather Extremes: Extreme weather conditions, such as wind or cold, may irritate the skin of patients using Adapt Gel.
    • Pediatric Use: Safety and effectiveness in children under 9 years have not been established.
  • Pregnancy & Lactation: Information regarding use during pregnancy and lactation is not provided in the original text. Always consult your doctor if you are pregnant, breastfeeding, or planning to be.
  • Interactions:
    • Adapalene: Increased irritation may occur if used with medicated or abrasive soaps, products with a strong drying effect, or those containing alcohol or astringents.
    • Benzoyl Peroxide: Products containing PABA (Para-aminobenzoic acid) sunscreens may temporarily discolor fabric when used with Benzoyl Peroxide.

 

Possible Side Effects (Adverse Effects)

 

Very Common (more than 10% of users):

  • Stinging/burning (3-41%)
  • Dryness (1-41%)
  • Scaling (1-35%)
  • Redness (erythema) (1-27%)

Common (1-10% of users):

  • Contact dermatitis (3%)
  • Application site burning (2%)
  • Application site irritation (1%)
  • Skin irritation (1%)

 

How It Works (Mechanism of Action)

 

  • Adapalene: It binds to specific retinoic acid nuclear receptors, which helps normalize the differentiation of follicular epithelial cells. This, in turn, reduces the formation of microcomedones (the early lesions of acne).
  • Benzoyl Peroxide: It has mild keratolytic (skin-peeling) effects and antimicrobial activity due to its oxidative properties. It is effective against S. epidermidis and P. acnes, common bacteria associated with acne.

Disclaimer: This information about Adapt Gel is for general knowledge and informational purposes only. It is not intended for diagnosis, medical advice, or treatment, and should not be a substitute for professional medical judgment. Always consult a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.

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