₨ NPR
Acnecure
Acnecure Gel, manufactured by Aadee Remedies Pvt. Ltd., contains Clindamycin 1% w/w as its active ingredient. It is available in Nepal as a 10 gm gel, with a retail price of 115.00 NPR.
Indications
Acnecure Gel is used for the topical treatment of various skin conditions, including:
- Acne vulgaris
- Erythrasma
- Rosacea
- Periorificial dermatitis
- Folliculitis
- Stasis dermatitis
- Chronic lymphedema
- Familial pemphigus
- Dermal ulcers
₨115.00
Ask about productDescription
Acnecure Gel is contraindicated in patients with a known hypersensitivity to clindamycin.
Precautions
- This product is not for oral, ophthalmic, or intravaginal use.
- Avoid exposure to sunlight and sunlamps while using this gel. Wear sunscreen daily.
- Lactation: Excretion in breast milk is unknown; use with caution.
Interactions
- May enhance the action of neuromuscular blocking agents (e.g., atracurium).
- May antagonize the effects of parasympathomimetics.
- May competitively inhibit the effects of macrolides, ketolides, streptogramins, linezolid, and chloramphenicol.
- May lead to increased coagulation tests (prothrombin time/INR) and/or bleeding with vitamin K antagonists (e.g., warfarin, acenocoumarol, fluindione).
Adverse Effects
- Common (greater than 10%): Dryness (18-23%), Oiliness (1-18%), Erythema (7-16%), Peeling (7-11%), Burning/itching (6-11%).
- Less Common (1-10%): Headache (3%).
Mechanism of Action
Clindamycin inhibits bacterial protein synthesis by reversibly binding to the 50S subunit of the ribosomal, thereby blocking the transpeptidation or translocation reactions in susceptible organisms. This results in stunted bacterial cell growth.
Additional information
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